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Maternal Alcohol Consumption during Pregnancy and Early Age Leukemia Risk in Brazil
Joint Authors
Ferreira, Jeniffer Dantas
Couto, Arnaldo Cézar
Emerenciano, Mariana
Koifman, Sergio
Pombo-de-Oliveira, Maria S.
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-18
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Objectives.
To investigate the association between the maternal alcohol consumption during pregnancy and early age leukemia (EAL) in offspring.
Methods.
Datasets were analyzed from a case-control study carried out in Brazil during 1999–2007.
Data were obtained by maternal interviews using a standardized questionnaire.
The present study included 675 children (193 acute lymphoid leukemia (ALL), 59 acute myeloid leukemia (AML), and 423 controls).
Unconditional logistic regression was performed, and adjusted odds ratios (adj.
OR) on the association between alcohol consumption and EAL were ascertained.
Results.
Alcohol consumption was reported by 43% of ALL and 39% of AML case mothers and 35.5% of controls’.
Beer consumption before and during pregnancy was associated with ALL in crude analysis (OR = 1.54, 95% CI, 1.08–2.19), although in adjusted analysis no statistical significance was found.
For weekly intake of ≤1 glass (adj.
OR = 1.30, 95% CI, 0.71–2.36) and ≥1 glass/week (adj.
OR = 1.47, 95% CI, 0.88–2.46) a potential dose-response was observed ( P trend < 0.03).
Conclusion.
This study failed to support the hypothesis of an increased risk of EAL associated with maternal alcohol intake during pregnancy, neither with the interaction with tobacco nor with alcohol consumption.
American Psychological Association (APA)
Ferreira, Jeniffer Dantas& Couto, Arnaldo Cézar& Emerenciano, Mariana& Pombo-de-Oliveira, Maria S.& Koifman, Sergio. 2015. Maternal Alcohol Consumption during Pregnancy and Early Age Leukemia Risk in Brazil. BioMed Research International،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1056556
Modern Language Association (MLA)
Ferreira, Jeniffer Dantas…[et al.]. Maternal Alcohol Consumption during Pregnancy and Early Age Leukemia Risk in Brazil. BioMed Research International No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1056556
American Medical Association (AMA)
Ferreira, Jeniffer Dantas& Couto, Arnaldo Cézar& Emerenciano, Mariana& Pombo-de-Oliveira, Maria S.& Koifman, Sergio. Maternal Alcohol Consumption during Pregnancy and Early Age Leukemia Risk in Brazil. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1056556
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1056556