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Latent Tuberculosis Infection among a Large Cohort of Medical Students at a Teaching Hospital in Italy
Joint Authors
Durando, Paolo
Alicino, Cristiano
Orsi, Andrea
Barberis, Ilaria
Paganino, Chiara
Dini, Guglielmo
Mazzarello, Giovanni
Del Bono, Valerio
Viscoli, Claudio
Copello, Francesco
Sossai, Dimitri
Orengo, Giovanni
Sticchi, Laura
Ansaldi, Filippo
Icardi, Giancarlo
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-02-01
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The surveillance of latent tuberculosis infection (LTBI) in both healthcare workers and healthcare students is considered fundamental for tuberculosis (TB) prevention.
The aim of the present study was to estimate LTBI prevalence and evaluate potential risk-factors associated with this condition in a large cohort of medical students in Italy.
In a cross-sectional study, performed between March and December 2012, 1511 eligible subjects attending the Medical School of the University of Genoa, trained at the IRCCS San Martino-IST Teaching Hospital of Genoa, were actively called to undergo the tuberculin skin test (TST).
All the TST positive cases were confirmed with an interferon-gamma release assay (IGRA).
A standardized questionnaire was collected for multivariate risk analysis.
A total of 1302 (86.2%) students underwent TST testing and completed the questionnaire.
Eleven subjects (0.8%) resulted TST positive and LTBI diagnosis was confirmed in 2 (0.1%) cases.
Professional exposure to active TB patients (OR 21.7, 95% CI 2.9–160.2; P value 0.003) and previous BCG immunization (OR 28.3, 95% CI 3.0–265.1; P value 0.003) are independently associated with TST positivity.
Despite the low prevalence of LTBI among Italian medical students, an occupational risk of TB infection still exists in countries with low circulation of Mycobacterium tuberculosis.
American Psychological Association (APA)
Durando, Paolo& Alicino, Cristiano& Orsi, Andrea& Barberis, Ilaria& Paganino, Chiara& Dini, Guglielmo…[et al.]. 2015. Latent Tuberculosis Infection among a Large Cohort of Medical Students at a Teaching Hospital in Italy. BioMed Research International،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1056599
Modern Language Association (MLA)
Durando, Paolo…[et al.]. Latent Tuberculosis Infection among a Large Cohort of Medical Students at a Teaching Hospital in Italy. BioMed Research International No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1056599
American Medical Association (AMA)
Durando, Paolo& Alicino, Cristiano& Orsi, Andrea& Barberis, Ilaria& Paganino, Chiara& Dini, Guglielmo…[et al.]. Latent Tuberculosis Infection among a Large Cohort of Medical Students at a Teaching Hospital in Italy. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1056599
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1056599