The Formation of Biofilms by Pseudomonas aeruginosa: A Review of the Natural and Synthetic Compounds Interfering with Control Mechanisms
Joint Authors
Rasamiravaka, Tsiry
Labtani, Quentin
Duez, Pierre
El Jaziri, Mondher
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-17, 17 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-03-19
Country of Publication
Egypt
No. of Pages
17
Main Subjects
Abstract EN
P.
aeruginosa is an opportunistic pathogenic bacterium responsible for both acute and chronic infections.
Beyond its natural resistance to many drugs, its ability to form biofilm, a complex biological system, renders ineffective the clearance by immune defense systems and antibiotherapy.
The objective of this report is to provide an overview (i) on P.
aeruginosa biofilm lifestyle cycle, (ii) on the main key actors relevant in the regulation of biofilm formation by P.
aeruginosa including QS systems, GacS/GacA and RetS/LadS two-component systems and C-di-GMP-dependent polysaccharides biosynthesis, and (iii) finally on reported natural and synthetic products that interfere with control mechanisms of biofilm formation by P.
aeruginosa without affecting directly bacterial viability.
Concluding remarks focus on perspectives to consider biofilm lifestyle as a target for eradication of resistant infections caused by P.
aeruginosa.
American Psychological Association (APA)
Rasamiravaka, Tsiry& Labtani, Quentin& Duez, Pierre& El Jaziri, Mondher. 2015. The Formation of Biofilms by Pseudomonas aeruginosa: A Review of the Natural and Synthetic Compounds Interfering with Control Mechanisms. BioMed Research International،Vol. 2015, no. 2015, pp.1-17.
https://search.emarefa.net/detail/BIM-1056652
Modern Language Association (MLA)
Rasamiravaka, Tsiry…[et al.]. The Formation of Biofilms by Pseudomonas aeruginosa: A Review of the Natural and Synthetic Compounds Interfering with Control Mechanisms. BioMed Research International No. 2015 (2015), pp.1-17.
https://search.emarefa.net/detail/BIM-1056652
American Medical Association (AMA)
Rasamiravaka, Tsiry& Labtani, Quentin& Duez, Pierre& El Jaziri, Mondher. The Formation of Biofilms by Pseudomonas aeruginosa: A Review of the Natural and Synthetic Compounds Interfering with Control Mechanisms. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-17.
https://search.emarefa.net/detail/BIM-1056652
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1056652