Molecular Targets in Alzheimer’s Disease: From Pathogenesis to Therapeutics
Joint Authors
Cheng, Xuan
Zhang, Lu
Lian, Ya-Jun
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-11-19
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Alzheimer’s disease (AD) is characterized by progressive cognitive decline usually beginning with impairment in the ability to form recent memories.
Nonavailability of definitive therapeutic strategy urges developing pharmacological targets based on cell signaling pathways.
A great revival of interest in nutraceuticals and adjuvant therapy has been put forward.
Tea polyphenols for their multiple health benefits have also attracted the attention of researchers.
Tea catechins showed enough potentiality to be used in future as therapeutic targets to provide neuroprotection against AD.
This review attempts to present a concise map of different receptor signaling pathways associated with AD with an insight into drug designing based on the proposed signaling pathways, molecular mechanistic details of AD pathogenesis, and a scientific rationale for using tea polyphenols as proposed therapeutic agents in AD.
American Psychological Association (APA)
Cheng, Xuan& Zhang, Lu& Lian, Ya-Jun. 2015. Molecular Targets in Alzheimer’s Disease: From Pathogenesis to Therapeutics. BioMed Research International،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1056659
Modern Language Association (MLA)
Cheng, Xuan…[et al.]. Molecular Targets in Alzheimer’s Disease: From Pathogenesis to Therapeutics. BioMed Research International No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1056659
American Medical Association (AMA)
Cheng, Xuan& Zhang, Lu& Lian, Ya-Jun. Molecular Targets in Alzheimer’s Disease: From Pathogenesis to Therapeutics. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1056659
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1056659