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Hearing Assessment after Treatment of Nasopharyngeal Carcinoma with CRT and IMRT Techniques
Joint Authors
Fang, Fu-Min
Zhuo, Ming-Ying
Yang, Chao-Hui
Yang, Li-Na
Hsieh, Hui-Shan
Hwang, Chung-Feng
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-08-16
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Objectives.
This study analyzed the long-term hearing loss after treatment of primary nasopharyngeal carcinoma to elucidate its causal factors.
Methods.
Ninety-two nasopharyngeal carcinoma patients were treated with radiotherapy or chemoradiotherapy.
Pure tone audiometry was performed before the therapy and annually up to 9 years after completing treatment.
The hearing thresholds were corrected for age-related deterioration and compared to the results without adjusting for age.
Results.
The mean air and bone conduction threshold with and without correction for age-related deterioration differed significantly 2–9 years after completing radiotherapy p < 0.05 .
The audiometry results with age correction showed a flattened configuration compared to the results without age correction.
The total radiation dose and radiation modality showed a causal relationship with a greater incidence of hearing loss after therapy p < 0.05 .
There was more deterioration in the air and bone hearing thresholds with conformal radiotherapy than intensity-modulated radiotherapy p < 0.001 .
A radiation dose >72 cGy resulted in more severe hearing loss than <72 cGy p < 0.05 .
Conclusion.
Hearing loss after completing therapy should be corrected for age-related hearing deterioration to reveal the true extent to which the loss is a therapeutic complication.
Both the radiation modality used and the dose were significantly associated with hearing loss.
American Psychological Association (APA)
Hwang, Chung-Feng& Fang, Fu-Min& Zhuo, Ming-Ying& Yang, Chao-Hui& Yang, Li-Na& Hsieh, Hui-Shan. 2015. Hearing Assessment after Treatment of Nasopharyngeal Carcinoma with CRT and IMRT Techniques. BioMed Research International،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1056689
Modern Language Association (MLA)
Hwang, Chung-Feng…[et al.]. Hearing Assessment after Treatment of Nasopharyngeal Carcinoma with CRT and IMRT Techniques. BioMed Research International No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1056689
American Medical Association (AMA)
Hwang, Chung-Feng& Fang, Fu-Min& Zhuo, Ming-Ying& Yang, Chao-Hui& Yang, Li-Na& Hsieh, Hui-Shan. Hearing Assessment after Treatment of Nasopharyngeal Carcinoma with CRT and IMRT Techniques. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1056689
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1056689