The Role of Overweight and Obesity in In Vitro Fertilization Outcomes of Poor Ovarian Responders
Joint Authors
Vural, Fisun
Vural, Birol
Çakıroğlu, Yiğit
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-27
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Objective.
Obesity is a worldwide concern with detrimental health effects including decreased fecundity.
However, obesity’s impact on in vitro fertilization (IVF) is inconclusive and there is little data concerning poor ovarian responders (POR).
This study explored the effects of overweight and obesity on IVF outcomes of POR.
Design.
We retrospectively evaluated 188 POR undergoing IVF cycles.
Methods.
Patients were categorized into three groups.
Group 1 was normal weight POR (18.5–24.9 kg/m2, n=96); Group 2 was overweight POR (25.0–29.9 kg/m2, n=52); and Group 3 was obese POR (≥30.0 kg/m2, n=40).
Main measured outcomes included IVF outcomes.
Results.
The oocyte maturity, total gonadotropin dose-duration, and cycle cancellation rates were similar.
Obese women had significantly decreased LH levels.
LH < 4 mIU/mL had a sensitivity (62%) and a specificity (86%) for IVF failure (AUC: 0.71).
Fertilization rates of obese subjects were significantly lower than normal and overweight subjects (p=0.04).
Obese women’s clinical pregnancy rates were significantly lower (15%) than normal weight women (33.3%, p=0.01).
Conclusions.
Despite similar counts of recruited mature oocytes, obese POR women had decreased fertilization and clinical pregnancy rates.
Obesity rather than overweight significantly decreased IVF outcomes in POR.
American Psychological Association (APA)
Vural, Fisun& Vural, Birol& Çakıroğlu, Yiğit. 2015. The Role of Overweight and Obesity in In Vitro Fertilization Outcomes of Poor Ovarian Responders. BioMed Research International،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1056701
Modern Language Association (MLA)
Vural, Fisun…[et al.]. The Role of Overweight and Obesity in In Vitro Fertilization Outcomes of Poor Ovarian Responders. BioMed Research International No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1056701
American Medical Association (AMA)
Vural, Fisun& Vural, Birol& Çakıroğlu, Yiğit. The Role of Overweight and Obesity in In Vitro Fertilization Outcomes of Poor Ovarian Responders. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1056701
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1056701