Prognostic Significance of NT-proBNP Levels in Patients over 65 Presenting Acute Myocardial Infarction Treated Invasively or Conservatively
Joint Authors
Drewniak, Wojciech
Szybka, Wojciech
Bielecki, Dariusz
Malinowski, Michal
Kotlarska, Joanna
Krol-Jaskulska, Agnieszka
Popielarz-Grygalewicz, Agata
Konwicka, Aleksandra
Dąbrowski, Marek
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-11
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objectives.
Assessment of prognostic significance of NT-proBNP level and the effects of invasive (I) and conservative (C) treatment of acute myocardial infarction (AMI) in patients over 65.
Materials and Methods.
One-year survival was assessed in 286 consecutive patients with AMI aged 65–100 (79 ± 8) subjected to I or C treatment (136 and 150 individuals), respectively.
Results.
245 (85%) patients survived in-hospital stay: 124 (91.1%) received I treatment and 121 (80.6%) received C treatment.
Heart failure (HF) was diagnosed in 30 patients receiving I treatment (22.6%) and in 71 subjected to C treatment (47.3%), p < 0,0001.
NT-proBNP levels in the latter group were significantly higher than in the 185 patients without HF (12311 ± 13560 pg/mL versus 4773 ± 8807 pg/mL, p < 0.0001).
NT-proBNP levels after coronary angioplasty were lower than in patients receiving C treatment (5922 ± 10250 pg/mL versus 8718 ± 12024 pg/mL, p = 0.0002).
Left ventricular ejection fraction was significantly higher in I patients than in C patients (47 ± 13% versus 42 ± 11.6%, p = 0.004).
During the one-year follow-up, 82.3% of I patients and 61.2% of the C patients survived (p < 0.0003).
There was a significantly lower probability of death at NT-proBNP below 8548.5 pg/mL.
Conclusions.
The NT-proBNP level in the first day of AMI is a good prognosticator.
One-year follow-up prognosis for patients who received I treatment in the AMI is better than that for C patients.
I patients exhibit superior left ventricular function after angioplasty and in the follow-up.
American Psychological Association (APA)
Drewniak, Wojciech& Szybka, Wojciech& Bielecki, Dariusz& Malinowski, Michal& Kotlarska, Joanna& Krol-Jaskulska, Agnieszka…[et al.]. 2015. Prognostic Significance of NT-proBNP Levels in Patients over 65 Presenting Acute Myocardial Infarction Treated Invasively or Conservatively. BioMed Research International،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1056702
Modern Language Association (MLA)
Drewniak, Wojciech…[et al.]. Prognostic Significance of NT-proBNP Levels in Patients over 65 Presenting Acute Myocardial Infarction Treated Invasively or Conservatively. BioMed Research International No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1056702
American Medical Association (AMA)
Drewniak, Wojciech& Szybka, Wojciech& Bielecki, Dariusz& Malinowski, Michal& Kotlarska, Joanna& Krol-Jaskulska, Agnieszka…[et al.]. Prognostic Significance of NT-proBNP Levels in Patients over 65 Presenting Acute Myocardial Infarction Treated Invasively or Conservatively. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1056702
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1056702