![](/images/graphics-bg.png)
Risk Factors of the Invasive Breast Cancer Locoregional Recurrence
Joint Authors
Liubota, R. V.
Zotov, A. S.
Vereshchako, R. I.
Liubota, I. I.
Zaychuk, V. V.
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-08-03
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background.
The aim of the research was to estimate the frequency of the locoregional breast cancer recurrence appearance, the recurrence-free period continuance, and the 3- and 5-year survival depending on the scope of the surgical intervention, menstrual profile, and histological and molecular-biologic characteristics of the primary tumor.
Patients and Methods.
Among 218 patients with a breast cancer, 99 patients had breast-conserving surgery (BCS) and 119 underwent radical mastectomy (RME); all patients had regional lymphatic nodes dissection.
The size and the primary tumor differentiation degree, metastasis presence in the regional lymph nodes, ER expression, PR, and Her/2neu were assessed as the prognostics factors.
Results.
It was defined that the locoregional recurrence appearance frequency in patients with BCS turned out to be 13%, and in patients after RME it turned out to be 9%; the recurrence-free period continuance was 53 ± 8 months and 56 ± 10 months, respectively.
Conclusions.
The locoregional cancer recurrence frequency is higher in women with the menstrual function being preserved at the moment of the primary tumor detection than in postmenopausal patients and also in patients having the hyperexpression of the Her/2neu.
The ipsilateral cancer recurrence decreases the 3-year survival by 7,1% and the 5-year one by 20,3%, respectively.
American Psychological Association (APA)
Liubota, R. V.& Zotov, A. S.& Vereshchako, R. I.& Liubota, I. I.& Zaychuk, V. V.. 2015. Risk Factors of the Invasive Breast Cancer Locoregional Recurrence. BioMed Research International،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1056730
Modern Language Association (MLA)
Liubota, R. V.…[et al.]. Risk Factors of the Invasive Breast Cancer Locoregional Recurrence. BioMed Research International No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1056730
American Medical Association (AMA)
Liubota, R. V.& Zotov, A. S.& Vereshchako, R. I.& Liubota, I. I.& Zaychuk, V. V.. Risk Factors of the Invasive Breast Cancer Locoregional Recurrence. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1056730
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1056730