Beyond the Immune Suppression: The Immunotherapy in Prostate Cancer
Joint Authors
Silvestri, Ida
Cattarino, Susanna
Aglianò, Anna Maria
Collalti, Giulia
Sciarra, Alessandro
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-06-16
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Prostate cancer (PCa) is the second most common cancer in men.
As well in many other human cancers, inflammation and immune suppression have an important role in their development.
We briefly describe the host components that interact with the tumor to generate an immune suppressive environment involved in PCa promotion and progression.
Different tools provide to overcome the mechanisms of immunosuppression including vaccines and immune checkpoint blockades.
With regard to this, we report results of most recent clinical trials investigating immunotherapy in metastatic PCa (Sipuleucel-T, ipilimumab, tasquinimod, Prostvac-VF, and GVAX) and provide possible future perspectives combining the immunotherapy to the traditional therapies.
American Psychological Association (APA)
Silvestri, Ida& Cattarino, Susanna& Aglianò, Anna Maria& Collalti, Giulia& Sciarra, Alessandro. 2015. Beyond the Immune Suppression: The Immunotherapy in Prostate Cancer. BioMed Research International،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1056754
Modern Language Association (MLA)
Silvestri, Ida…[et al.]. Beyond the Immune Suppression: The Immunotherapy in Prostate Cancer. BioMed Research International No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1056754
American Medical Association (AMA)
Silvestri, Ida& Cattarino, Susanna& Aglianò, Anna Maria& Collalti, Giulia& Sciarra, Alessandro. Beyond the Immune Suppression: The Immunotherapy in Prostate Cancer. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1056754
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1056754