![](/images/graphics-bg.png)
Comparison of Fine Needle Aspiration and Fine Needle Nonaspiration Cytology of Thyroid Nodules: A Meta-Analysis
Joint Authors
Song, Hongming
Wei, Chuankui
Li, Dengfeng
Hua, Kaiyao
Song, Jialu
Maskey, Niraj
Fang, Lin
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-09-29
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Background.
Fine needle aspiration cytology (FNAC) and fine needle nonaspiration cytology (FNNAC) are useful cost-effective techniques for preoperatively assessing thyroid lesions.
Both techniques have advantages and disadvantages, and there is controversy over which method is superior.
This meta-analysis was performed to evaluate the differences between FNAC and FNNAC for diagnosis of thyroid nodules.
Methods.
Primary publications were independently collected by two reviewers from PubMed, Web of Science, Google Scholar, EBSCO, OALib, and the Cochrane Library databases.
The following search terms were used: fine needle, aspiration, capillary, nonaspiration, sampling without aspiration, thyroid, and cytology.
The last search was performed on February 1, 2015.
Results.
Sixteen studies comprising 1,842 patients and 2,221 samples were included in this study.
No statistically significant difference was observed between FNAC and FNNAC groups with respect to diagnostically inadequate smears, diagnostically superior smears, diagnostic performance (accuracy, sensitivity, specificity, negative predictive value, and positive predictive value), area under the summary receiver operating characteristic curve, average score of each parameter (background blood or clot, amount of cellular material, degree of cellular degeneration, degree of cellular trauma, and retention of appropriate architecture), and total score of five parameters.
Conclusion.
FNAC and FNNAC are equally useful in assessing thyroid nodules.
American Psychological Association (APA)
Song, Hongming& Wei, Chuankui& Li, Dengfeng& Hua, Kaiyao& Song, Jialu& Maskey, Niraj…[et al.]. 2015. Comparison of Fine Needle Aspiration and Fine Needle Nonaspiration Cytology of Thyroid Nodules: A Meta-Analysis. BioMed Research International،Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1056759
Modern Language Association (MLA)
Song, Hongming…[et al.]. Comparison of Fine Needle Aspiration and Fine Needle Nonaspiration Cytology of Thyroid Nodules: A Meta-Analysis. BioMed Research International No. 2015 (2015), pp.1-13.
https://search.emarefa.net/detail/BIM-1056759
American Medical Association (AMA)
Song, Hongming& Wei, Chuankui& Li, Dengfeng& Hua, Kaiyao& Song, Jialu& Maskey, Niraj…[et al.]. Comparison of Fine Needle Aspiration and Fine Needle Nonaspiration Cytology of Thyroid Nodules: A Meta-Analysis. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-13.
https://search.emarefa.net/detail/BIM-1056759
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1056759