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Using Regional Homogeneity to Reveal Altered Spontaneous Activity in Patients with Mild Cognitive Impairment
Joint Authors
Wang, Yumei
Zhao, Xiaochuan
Xu, Shunjiang
Yu, Lulu
Wang, Lan
Song, Mei
Yang, Linlin
Wang, Xueyi
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-02-09
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Most patients with mild cognitive impairment (MCI) are thought to be in an early stage of Alzheimer’s disease (AD).
Resting-state functional magnetic resonance imaging reflects spontaneous brain activity and/or the endogenous/background neurophysiological process of the human brain.
Regional homogeneity (ReHo) rapidly maps regional brain activity across the whole brain.
In the present study, we used the ReHo index to explore whole brain spontaneous activity pattern in MCI.
Our results showed that MCI subjects displayed an increased ReHo index in the paracentral lobe, precuneus, and postcentral and a decreased ReHo index in the medial temporal gyrus and hippocampus.
Impairments in the medial temporal gyrus and hippocampus may serve as important markers distinguishing MCI from healthy aging.
Moreover, the increased ReHo index observed in the postcentral and paracentral lobes might indicate compensation for the cognitive function losses in individuals with MCI.
American Psychological Association (APA)
Wang, Yumei& Zhao, Xiaochuan& Xu, Shunjiang& Yu, Lulu& Wang, Lan& Song, Mei…[et al.]. 2015. Using Regional Homogeneity to Reveal Altered Spontaneous Activity in Patients with Mild Cognitive Impairment. BioMed Research International،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1056796
Modern Language Association (MLA)
Wang, Yumei…[et al.]. Using Regional Homogeneity to Reveal Altered Spontaneous Activity in Patients with Mild Cognitive Impairment. BioMed Research International No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1056796
American Medical Association (AMA)
Wang, Yumei& Zhao, Xiaochuan& Xu, Shunjiang& Yu, Lulu& Wang, Lan& Song, Mei…[et al.]. Using Regional Homogeneity to Reveal Altered Spontaneous Activity in Patients with Mild Cognitive Impairment. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1056796
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1056796