![](/images/graphics-bg.png)
Kidney Injury Molecule-1 and Cardiovascular Diseases: From Basic Science to Clinical Practice
Joint Authors
Basta-Jovanovic, Gordana
Medić, Branislava
Rovčanin, Branislav
Radojević-Škodrić, Sanja
Prostran, Milica
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-11-30
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Despite the recent findings concerning pathogenesis and novel therapeutic strategies, cardiovascular disease (CVD) still stays the leading cause of morbidity and mortality in patients with renal dysfunction, especially acute kidney injury (AKI).
Early detection of patients with impaired renal function with cardiovascular risk may help ensure more aggressive treatment and improve clinical outcome.
Kidney injury molecule-1 (KIM-1) is a new, promising marker of kidney damage which is currently the focus of countless studies worldwide.
Some recent animal and human studies established KIM-1 as an important marker of acute tubular necrosis (ATN) and reliable predictor of development and prognosis of AKI.
Food and Drug Administration (FDA) in USA acclaimed KIM-1 as an AKI biomarker for preclinical drug development.
Recent data suggest the importance of monitoring of KIM-1 for early diagnosis and clinical course not only in patients with various forms of AKI and other renal diseases but also in patients with cardiorenal syndrome, heart failure, cardiopulmonary bypass, cardiothoracic surgical interventions in the pediatric emergency setting, and so forth.
The aim of this review article is to summarize the literature data concerning KIM-1 as a potential novel marker in the early diagnosis and prediction of clinical outcome of certain cardiovascular diseases.
American Psychological Association (APA)
Medić, Branislava& Rovčanin, Branislav& Basta-Jovanovic, Gordana& Radojević-Škodrić, Sanja& Prostran, Milica. 2015. Kidney Injury Molecule-1 and Cardiovascular Diseases: From Basic Science to Clinical Practice. BioMed Research International،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1057017
Modern Language Association (MLA)
Medić, Branislava…[et al.]. Kidney Injury Molecule-1 and Cardiovascular Diseases: From Basic Science to Clinical Practice. BioMed Research International No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1057017
American Medical Association (AMA)
Medić, Branislava& Rovčanin, Branislav& Basta-Jovanovic, Gordana& Radojević-Škodrić, Sanja& Prostran, Milica. Kidney Injury Molecule-1 and Cardiovascular Diseases: From Basic Science to Clinical Practice. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1057017
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1057017