Preparative Purification of Liriodendrin from Sargentodoxa cuneata by Macroporous Resin
Joint Authors
Li, Di-Hua
Wang, Yan
Lv, Yuan-Shan
Liu, Jun-Hong
Yang, Lei
Zhang, Shu-Kun
Zhuo, Yu-Zhen
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-07-07
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The preparative purification of liriodendrin from Sargentodoxa cuneata using macroporous resin combined with crystallization process was evaluated.
The properties of adsorption/desorption of liriodendrin on eight macroporous resins were investigated systematically.
X-5 resin was selected as the most suitable medium for liriodendrin purification.
The adsorption of liriodendrin on X-5 resin fitted well with the pseudo-second-order kinetic model and Langmuir isotherm model.
Dynamic adsorption/desorption tests were performed using a glass column packed with X-5 resin to optimize the separation process of liriodendrin.
After one treatment with X-5 resin, the content of liriodendrin in the product was increased 48.73-fold, from 0.85% to 41.42%, with a recovery yield of 88.9%.
97.48% liriodendrin was obtained by further crystallization and determined by HPLC.
The purified product possessed strong antioxidant activity.
In conclusion, purification of liriodendrin might expend its further pharmacological researches and further applications in pharmacy.
American Psychological Association (APA)
Li, Di-Hua& Wang, Yan& Lv, Yuan-Shan& Liu, Jun-Hong& Yang, Lei& Zhang, Shu-Kun…[et al.]. 2015. Preparative Purification of Liriodendrin from Sargentodoxa cuneata by Macroporous Resin. BioMed Research International،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1057045
Modern Language Association (MLA)
Li, Di-Hua…[et al.]. Preparative Purification of Liriodendrin from Sargentodoxa cuneata by Macroporous Resin. BioMed Research International No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1057045
American Medical Association (AMA)
Li, Di-Hua& Wang, Yan& Lv, Yuan-Shan& Liu, Jun-Hong& Yang, Lei& Zhang, Shu-Kun…[et al.]. Preparative Purification of Liriodendrin from Sargentodoxa cuneata by Macroporous Resin. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1057045
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1057045