Outcome of Elderly Patients with Meningioma after Image-Guided Stereotactic Radiotherapy: A Study of 100 Cases
Joint Authors
Kaul, David
Budach, Volker
Graaf, Lukas
Gollrad, Johannes
Badakhshi, Harun
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-26
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Introduction.
Incidence of meningioma increases with age.
Surgery has been the mainstay treatment.
Elderly patients, however, are at risk of severe morbidity.
Therefore, we conducted this study to analyze long-term outcomes of linac-based fractionated stereotactic radiotherapy (FSRT) for older adults (aged ≥65 years) with meningioma and determine prognostic factors.
Materials and Methods.
Between October 1998 and March 2009, 100 patients (≥65, median age, 71 years) were treated with FSRT for meningioma.
Two patients were lost to follow-up.
Eight patients each had grade I and grade II meningiomas, and five patients had grade III meningiomas.
The histology was unknown in 77 cases (grade 0).
Results.
The median follow-up was 37 months, and 3-year, 5-year, and 10-year progression-free survival (PFS) rates were 93.7%, 91.1%, and 82%.
Patients with grade 0/I meningioma showed 3- and 5-year PFS rates of 98.4% and 95.6%.
Patients with grade II or III meningiomas showed 3-year PFS rates of 36%.
93.8% of patients showed local tumor control.
Multivariate analysis did not indicate any significant prognostic factors.
Conclusion.
FSRT may play an important role as a noninvasive and safe method in the clinical management of older patients with meningioma.
American Psychological Association (APA)
Kaul, David& Budach, Volker& Graaf, Lukas& Gollrad, Johannes& Badakhshi, Harun. 2015. Outcome of Elderly Patients with Meningioma after Image-Guided Stereotactic Radiotherapy: A Study of 100 Cases. BioMed Research International،Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1057072
Modern Language Association (MLA)
Kaul, David…[et al.]. Outcome of Elderly Patients with Meningioma after Image-Guided Stereotactic Radiotherapy: A Study of 100 Cases. BioMed Research International No. 2015 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1057072
American Medical Association (AMA)
Kaul, David& Budach, Volker& Graaf, Lukas& Gollrad, Johannes& Badakhshi, Harun. Outcome of Elderly Patients with Meningioma after Image-Guided Stereotactic Radiotherapy: A Study of 100 Cases. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-6.
https://search.emarefa.net/detail/BIM-1057072
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1057072