Orthostatic Intolerance Is Independent of the Degree of Autonomic Cardiovascular Adaptation after 60 Days of Head-Down Bed Rest
Joint Authors
Liu, Jiexin
Li, Yongzhi
Verheyden, Bart
Chen, Zhanghuang
Wang, Jingyu
Li, Yinghui
Aubert, André E.
Yuan, Ming
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-09-03
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Spaceflight and head-down bed rest (HDBR) can induce the orthostatic intolerance (OI); the mechanisms remain to be clarified.
The aim of this study was to determine whether or not OI after HDBR relates to the degree of autonomic cardiovascular adaptation.
Fourteen volunteers were enrolled for 60 days of HDBR.
A head-up tilt test (HUTT) was performed before and after HDBR.
Our data revealed that, in all nonfainters, there was a progressive increase in heart rate over the course of HDBR, which remained higher until 12 days of recovery.
The mean arterial pressure gradually increased until day 56 of HDBR and returned to baseline after 12 days of recovery.
Respiratory sinus arrhythmia and baroreflex sensitivity decreased during HDBR and remained suppressed until 12 days of recovery.
Low-frequency power of systolic arterial pressure increased during HDBR and remained elevated during recovery.
Three subjects fainted during the HUTT after HDBR, in which systemic vascular resistance did not increase and remained lower until syncope.
None of the circulatory patterns significantly differed between the fainters and the nonfainters at any time point.
In conclusion, our data indicate that the impaired orthostatic tolerance after HDBR could not be distinguished by estimation of normal hemodynamic and/or neurocardiac data.
American Psychological Association (APA)
Liu, Jiexin& Li, Yongzhi& Verheyden, Bart& Chen, Zhanghuang& Wang, Jingyu& Li, Yinghui…[et al.]. 2015. Orthostatic Intolerance Is Independent of the Degree of Autonomic Cardiovascular Adaptation after 60 Days of Head-Down Bed Rest. BioMed Research International،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1057154
Modern Language Association (MLA)
Liu, Jiexin…[et al.]. Orthostatic Intolerance Is Independent of the Degree of Autonomic Cardiovascular Adaptation after 60 Days of Head-Down Bed Rest. BioMed Research International No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1057154
American Medical Association (AMA)
Liu, Jiexin& Li, Yongzhi& Verheyden, Bart& Chen, Zhanghuang& Wang, Jingyu& Li, Yinghui…[et al.]. Orthostatic Intolerance Is Independent of the Degree of Autonomic Cardiovascular Adaptation after 60 Days of Head-Down Bed Rest. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1057154
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1057154