Novel Numerical Characterization of Protein Sequences Based on Individual Amino Acid and Its Application
Joint Authors
Zhang, Yanping
Ruan, Jishou
Sheng, Ya-jun
Zheng, Wei
He, Ping-an
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-02-02
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The hydrophobicity and hydrophilicity of amino acids play a very important role in protein folding and its interaction with the environment and other molecules, as well as its catalytic mechanism.
Based on the two physicochemical indexes, a 2D graphical representation of protein sequences is introduced; meanwhile, a new numerical characteristic has been proposed to compute the distance of different sequences for analysis of sequence similarity/dissimilarity on the basis of this graphical representation.
Furthermore, we apply the new distance in the similarities/dissimilarities of ND5 proteins of nine species and predict the four major classes based on the dataset containing 639 domains.
The results show that the method is simple and effective.
American Psychological Association (APA)
Zhang, Yanping& Sheng, Ya-jun& Zheng, Wei& He, Ping-an& Ruan, Jishou. 2015. Novel Numerical Characterization of Protein Sequences Based on Individual Amino Acid and Its Application. BioMed Research International،Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1057197
Modern Language Association (MLA)
Zhang, Yanping…[et al.]. Novel Numerical Characterization of Protein Sequences Based on Individual Amino Acid and Its Application. BioMed Research International No. 2015 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1057197
American Medical Association (AMA)
Zhang, Yanping& Sheng, Ya-jun& Zheng, Wei& He, Ping-an& Ruan, Jishou. Novel Numerical Characterization of Protein Sequences Based on Individual Amino Acid and Its Application. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-8.
https://search.emarefa.net/detail/BIM-1057197
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1057197