Constraint Programming Based Biomarker Optimization
Joint Authors
Zhou, Manli
Luo, Youxi
Sun, Guoquan
Mai, Guoqin
Zhou, Fengfeng
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-05
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Efficient and intuitive characterization of biological big data is becoming a major challenge for modern bio-OMIC based scientists.
Interactive visualization and exploration of big data is proven to be one of the successful solutions.
Most of the existing feature selection algorithms do not allow the interactive inputs from users in the optimizing process of feature selection.
This study investigates this question as fixing a few user-input features in the finally selected feature subset and formulates these user-input features as constraints for a programming model.
The proposed algorithm, fsCoP (feature selection based on constrained programming), performs well similar to or much better than the existing feature selection algorithms, even with the constraints from both literature and the existing algorithms.
An fsCoP biomarker may be intriguing for further wet lab validation, since it satisfies both the classification optimization function and the biomedical knowledge.
fsCoP may also be used for the interactive exploration of bio-OMIC big data by interactively adding user-defined constraints for modeling.
American Psychological Association (APA)
Zhou, Manli& Luo, Youxi& Sun, Guoquan& Mai, Guoqin& Zhou, Fengfeng. 2015. Constraint Programming Based Biomarker Optimization. BioMed Research International،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1057204
Modern Language Association (MLA)
Zhou, Manli…[et al.]. Constraint Programming Based Biomarker Optimization. BioMed Research International No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1057204
American Medical Association (AMA)
Zhou, Manli& Luo, Youxi& Sun, Guoquan& Mai, Guoqin& Zhou, Fengfeng. Constraint Programming Based Biomarker Optimization. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1057204
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1057204