Modeling the Generation of Phase-Amplitude Coupling in Cortical Circuits: From Detailed Networks to Neural Mass Models
Author
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-11
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Phase-amplitude coupling (PAC), the phenomenon where the amplitude of a high frequency oscillation is modulated by the phase of a lower frequency oscillation, is attracting an increasing interest in the neuroscience community due to its potential relevance for understanding healthy and pathological information processing in the brain.
PAC is a diverse phenomenon, having been experimentally detected in at least ten combinations of rhythms: delta-theta, delta-alpha, delta-beta, delta-gamma, theta-alpha, theta-beta, theta-gamma, alpha-beta, alpha-gamma, and beta-gamma.
However, a complete understanding of the biophysical mechanisms generating this diversity is lacking.
Here we review computational models of PAC generation that range from detailed models of neuronal networks, where each cell is described by Hodgkin-Huxley-type equations, to neural mass models (NMMs) where only the average activities of neuronal populations are considered.
We argue that NMMs are an appropriate mathematical framework (due to the small number of parameters and variables involved and the richness of the dynamics they can generate) to study the PAC phenomenon.
American Psychological Association (APA)
Sotero, Roberto. 2015. Modeling the Generation of Phase-Amplitude Coupling in Cortical Circuits: From Detailed Networks to Neural Mass Models. BioMed Research International،Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1057222
Modern Language Association (MLA)
Sotero, Roberto. Modeling the Generation of Phase-Amplitude Coupling in Cortical Circuits: From Detailed Networks to Neural Mass Models. BioMed Research International No. 2015 (2015), pp.1-12.
https://search.emarefa.net/detail/BIM-1057222
American Medical Association (AMA)
Sotero, Roberto. Modeling the Generation of Phase-Amplitude Coupling in Cortical Circuits: From Detailed Networks to Neural Mass Models. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-12.
https://search.emarefa.net/detail/BIM-1057222
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1057222