Intramuscular Administration of Drotaverine Hydrochloride Decreases Both Incidence of Urinary Retention and Time to Micturition in Orthopedic Patients under Spinal Anesthesia: A Single Blinded Randomized Study
Joint Authors
Tomaszewski, Dariusz
Bałkota, Mariusz
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-06-21
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Purpose.
Postoperative urinary retention (POUR) increases the duration of hospitalization and frequency and risk of urinary bladder catheterization.
The objective of this study was to analyze the efficacy of intramuscularly administered drotaverine hydrochloride in the prevention of POUR in orthopedic patients.
Methods.
Two hundred and thirty patients 17–40 years of age undergoing lower limb orthopedic procedures under spinal anesthesia were enrolled in the study.
The study group received 40 mg of drotaverine hydrochloride intramuscularly; the second group was the control.
The main outcome measure was (1) the time to micturition and (2) the incidence of urinary bladder catheterization and time to catheterization.
Results.
Two hundred and one patients of 230 enrolled participants completed the study.
Compared to the control group, the male patients in study group exhibited a shorter time to spontaneous micturition (441 versus 563 minutes, 95% CI of the difference of means between 39 and 205 minutes) and a lower incidence of urinary bladder catheterization (4/75 versus 10/54) (RR 0.29, 95% CI: 0.1–0.87; P=0.0175).
Conclusions.
Intramuscular administration of drotaverine hydrochloride decreased the time to spontaneous micturition and decreased the incidence of urinary bladder catheterization in male patients who underwent orthopedic surgery under spinal anesthesia.
This trial is registered with NCT02026427.
American Psychological Association (APA)
Tomaszewski, Dariusz& Bałkota, Mariusz. 2015. Intramuscular Administration of Drotaverine Hydrochloride Decreases Both Incidence of Urinary Retention and Time to Micturition in Orthopedic Patients under Spinal Anesthesia: A Single Blinded Randomized Study. BioMed Research International،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1057271
Modern Language Association (MLA)
Tomaszewski, Dariusz& Bałkota, Mariusz. Intramuscular Administration of Drotaverine Hydrochloride Decreases Both Incidence of Urinary Retention and Time to Micturition in Orthopedic Patients under Spinal Anesthesia: A Single Blinded Randomized Study. BioMed Research International No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1057271
American Medical Association (AMA)
Tomaszewski, Dariusz& Bałkota, Mariusz. Intramuscular Administration of Drotaverine Hydrochloride Decreases Both Incidence of Urinary Retention and Time to Micturition in Orthopedic Patients under Spinal Anesthesia: A Single Blinded Randomized Study. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1057271
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1057271