Zoledronic Acid May Reduce Intraoperative Bleeding in Spinal Tumors: A Prospective Cohort Study
Joint Authors
Wu, Juan
Zheng, Wei
Tan, Yan
Hu, Xiao-Yuan
Huang, Quan
Fan, Kai-Hua
Ma, Jie
Xiao, Wen-Jing
Ren, Jian-Dong
Hou, Jun
Xiao, Jian-Ru
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-01-22
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Between June 2010 and June 2011, 176 patients were divided into 2 groups: a group with spinal metastasis of solid tumors (n=157) and a group with multiple myeloma (n=19).
Both groups were further divided into 2 subgroups: a group receiving zoledronic acid before surgery and a control group.
The zoledronic acid subgroup of the solid tumors group was group A (n=81), the control subgroup of the solid tumors group was group B (n=76), the zoledronic acid subgroup of the multiple myeloma group was group C (n=10), and the control subgroup of the multiple myeloma group was group D (n=9).
The average intraoperative blood loss during spinal surgery was as follows: 1311±691 mL in group A and 1752±740 mL in group B (P=0.000) and 1994±810 mL in group C and 3134±795 mL in group D (P=0.000).
Patients receiving zoledronic acid before surgery had significantly less intraoperative bleeding than those who did not receive it.
Preoperative use of zoledronic acid can effectively reduce intraoperative bleeding during surgery for the treatment of spinal tumors.
American Psychological Association (APA)
Wu, Juan& Zheng, Wei& Tan, Yan& Hu, Xiao-Yuan& Huang, Quan& Fan, Kai-Hua…[et al.]. 2015. Zoledronic Acid May Reduce Intraoperative Bleeding in Spinal Tumors: A Prospective Cohort Study. BioMed Research International،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1057303
Modern Language Association (MLA)
Wu, Juan…[et al.]. Zoledronic Acid May Reduce Intraoperative Bleeding in Spinal Tumors: A Prospective Cohort Study. BioMed Research International No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1057303
American Medical Association (AMA)
Wu, Juan& Zheng, Wei& Tan, Yan& Hu, Xiao-Yuan& Huang, Quan& Fan, Kai-Hua…[et al.]. Zoledronic Acid May Reduce Intraoperative Bleeding in Spinal Tumors: A Prospective Cohort Study. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1057303
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1057303