miR-1322 Binding Sites in Paralogous and Orthologous Genes
Joint Authors
Pyrkova, Anna
Niyazova, Raigul
Atambayeva, Shara
Alybayeva, Aigul
Ivashchenko, Anatoly
Berillo, Olga
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-31
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
We searched for 2,563 microRNA (miRNA) binding sites in 17,494 mRNA sequences of human genes.
miR-1322 has more than 2,000 binding sites in 1,058 genes with Δ G / Δ G m ratio of 85% and more.
miR-1322 has 1,889 binding sites in CDSs, 215 binding sites in 5′ UTRs, and 160 binding sites in 3′ UTRs.
From two to 28 binding sites have arranged localization with the start position through three nucleotides of each following binding site.
The nucleotide sequences of these sites in CDSs encode oligopeptides with the same and/or different amino acid sequences.
We found that 33% of the target genes encoded transcription factors.
miR-1322 has arranged binding sites in the CDSs of orthologous MAMLD1, MAML2, and MAML3 genes.
These sites encode a polyglutamine oligopeptide ranging from six to 47 amino acids in length.
The properties of miR-1322 binding sites in orthologous and paralogous target genes are discussed.
American Psychological Association (APA)
Niyazova, Raigul& Berillo, Olga& Atambayeva, Shara& Pyrkova, Anna& Alybayeva, Aigul& Ivashchenko, Anatoly. 2015. miR-1322 Binding Sites in Paralogous and Orthologous Genes. BioMed Research International،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1057398
Modern Language Association (MLA)
Niyazova, Raigul…[et al.]. miR-1322 Binding Sites in Paralogous and Orthologous Genes. BioMed Research International No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1057398
American Medical Association (AMA)
Niyazova, Raigul& Berillo, Olga& Atambayeva, Shara& Pyrkova, Anna& Alybayeva, Aigul& Ivashchenko, Anatoly. miR-1322 Binding Sites in Paralogous and Orthologous Genes. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1057398
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1057398