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QT Interval Variability Index and QT Interval Duration in Different Sleep Stages: Analysis of Polysomnographic Recordings in Nonapneic Male Patients
Joint Authors
Meigas, Kalju
Viigimae, Moonika
Karai, Deniss
Pirn, Peeter
Pilt, Kristjan
Kaik, Jyri
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-11-29
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The aim of the study was to determine whether different sleep stages, especially REM sleep, affect QT interval duration and variability in male patients without obstructive sleep apnea (OSA).
Polysomnographic recordings of 30 patients were analyzed.
Beat-to-beat QT interval variability was calculated using QTV index (QTVI) formula.
For QTc interval calculation, in addition to Bazett’s formula, linear and parabolic heart rate correction formulas with two separate α values were used.
QTVI and QTc values were calculated as means of 2 awake, 3 NREM, and 3 REM sleep episodes; the duration of each episode was 300 sec.
Mean QTVI values were not statistically different between sleep stages.
Therefore, elevated QTVI values found in patients with OSA cannot be interpreted as physiological sympathetic impact during REM sleep and should be considered as a risk factor for potentially life-threatening ventricular arrhythmias.
The absence of difference of the mean QTc interval values between NREM and REM stages seems to confirm our conclusion that sympathetic surges during REM stage do not induce repolarization variability.
In patients without notable structural and electrical remodeling of myocardium, physiological elevation in sympathetic activity during REM sleep remains subthreshold concerning clinically significant increase of myocardial electrical instability.
American Psychological Association (APA)
Viigimae, Moonika& Karai, Deniss& Pirn, Peeter& Pilt, Kristjan& Meigas, Kalju& Kaik, Jyri. 2015. QT Interval Variability Index and QT Interval Duration in Different Sleep Stages: Analysis of Polysomnographic Recordings in Nonapneic Male Patients. BioMed Research International،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1057402
Modern Language Association (MLA)
Viigimae, Moonika…[et al.]. QT Interval Variability Index and QT Interval Duration in Different Sleep Stages: Analysis of Polysomnographic Recordings in Nonapneic Male Patients. BioMed Research International No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1057402
American Medical Association (AMA)
Viigimae, Moonika& Karai, Deniss& Pirn, Peeter& Pilt, Kristjan& Meigas, Kalju& Kaik, Jyri. QT Interval Variability Index and QT Interval Duration in Different Sleep Stages: Analysis of Polysomnographic Recordings in Nonapneic Male Patients. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1057402
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1057402