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Biomaterials for Pelvic Floor Reconstructive Surgery: How Can We Do Better?
Joint Authors
MacNeil, Sheila
Chapple, Christopher R.
Roman Regueros, Sabiniano
Gigliobianco, Giulia
Bissoli, Julio
Osman, Nadir I.
Bullock, Anthony J.
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-20, 20 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-04-21
Country of Publication
Egypt
No. of Pages
20
Main Subjects
Abstract EN
Stress urinary incontinence (SUI) and pelvic organ prolapse (POP) are major health issues that detrimentally impact the quality of life of millions of women worldwide.
Surgical repair is an effective and durable treatment for both conditions.
Over the past two decades there has been a trend to enforce or reinforce repairs with synthetic and biological materials.
The determinants of surgical outcome are many, encompassing the physical and mechanical properties of the material used, and individual immune responses, as well surgical and constitutional factors.
Of the current biomaterials in use none represents an ideal.
Biomaterials that induce limited inflammatory response followed by constructive remodelling appear to have more long term success than biomaterials that induce chronic inflammation, fibrosis and encapsulation.
In this review we draw upon published animal and human studies to characterize the changes biomaterials undergo after implantation and the typical host responses, placing these in the context of clinical outcomes.
American Psychological Association (APA)
Gigliobianco, Giulia& Roman Regueros, Sabiniano& Osman, Nadir I.& Bissoli, Julio& Bullock, Anthony J.& Chapple, Christopher R.…[et al.]. 2015. Biomaterials for Pelvic Floor Reconstructive Surgery: How Can We Do Better?. BioMed Research International،Vol. 2015, no. 2015, pp.1-20.
https://search.emarefa.net/detail/BIM-1057422
Modern Language Association (MLA)
Gigliobianco, Giulia…[et al.]. Biomaterials for Pelvic Floor Reconstructive Surgery: How Can We Do Better?. BioMed Research International No. 2015 (2015), pp.1-20.
https://search.emarefa.net/detail/BIM-1057422
American Medical Association (AMA)
Gigliobianco, Giulia& Roman Regueros, Sabiniano& Osman, Nadir I.& Bissoli, Julio& Bullock, Anthony J.& Chapple, Christopher R.…[et al.]. Biomaterials for Pelvic Floor Reconstructive Surgery: How Can We Do Better?. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-20.
https://search.emarefa.net/detail/BIM-1057422
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1057422