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Structural and Function Correlation of Cone Packing Utilizing Adaptive Optics and Microperimetry
Joint Authors
Shetty, Rohit
Kurian Kummelil, Mathew
Hedge, Bharath
Mangalesh, Shwetha
Supriya, Dabir
Kiran Anupama, Kumar
Berendschot, Tos T. J. M.
Schouten, Jan S. A. G.
Bharamshetter, Roopa
Naresh, Yadav K.
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-06-08
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Aim.
To assess the functional aspects of cone mosaic and correlate cone packing with retinal sensitivity utilizing microperimetry in emmetropes at different eccentricities.
Methods.
Twenty-four healthy volunteers underwent microperimetry (MAIA Centervue, Italy) and assessment of photoreceptors using adaptive optics retinal camera, rtx1 (Imagine Eyes, Orsay, France), at 2 and 3 degrees from the foveal centre in 4 quadrants: superior, inferior, temporal, and nasal.
Data was analyzed using SPSS version 17 (IBM).
Spearman’s correlation tests were used to establish correlation between mean cone packing density and retinal sensitivity at different quadrants.
Results.
Thirteen females and 11 males (age range 20–40 years) were included.
The cone density was found to be significantly different among all quadrants (temporal = 25786.68/mm2 ± 4367.07/mm2, superior = 23009.35/mm2 ± 5415.81/mm2, nasal = 22838.09/mm2 ± 4166.22/mm2, and inferior = 21097.53/mm2 ± 4235.84/mm2).
A statistical significance P < 0.008 was found between orthogonal meridians, that is, temporal, nasal 48624.77 / m m 2 > superior, inferior (44106.88/mm2).
A drop in retinal sensitivity was observed as the eccentricity increased P < 0.05 .
It was also found that as cone packing density decreased retinal sensitivity also decreased P < 0.05 in all quadrants.
This was observed at both 2 and 3 degrees.
Conclusion.
It is of crucial importance to establish normative variations in cone structure-function correlation.
This may help in detection of subtle pathology and its early intervention.
American Psychological Association (APA)
Supriya, Dabir& Mangalesh, Shwetha& Kiran Anupama, Kumar& Kurian Kummelil, Mathew& Berendschot, Tos T. J. M.& Schouten, Jan S. A. G.…[et al.]. 2015. Structural and Function Correlation of Cone Packing Utilizing Adaptive Optics and Microperimetry. BioMed Research International،Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1057426
Modern Language Association (MLA)
Supriya, Dabir…[et al.]. Structural and Function Correlation of Cone Packing Utilizing Adaptive Optics and Microperimetry. BioMed Research International No. 2015 (2015), pp.1-4.
https://search.emarefa.net/detail/BIM-1057426
American Medical Association (AMA)
Supriya, Dabir& Mangalesh, Shwetha& Kiran Anupama, Kumar& Kurian Kummelil, Mathew& Berendschot, Tos T. J. M.& Schouten, Jan S. A. G.…[et al.]. Structural and Function Correlation of Cone Packing Utilizing Adaptive Optics and Microperimetry. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1057426
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1057426