Effects of Atrazine on the Development of Neural System of Zebrafish, Danio rerio
Joint Authors
Wang, Hao
Mu, Shumei
Zhang, Fengjuan
Wang, Hailing
Liu, Huan
Zhang, Han
Kang, Xianjiang
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-31
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
By comparative analysis of histomorphology and AChE activity, the changes of physiological and biochemical parameters were determined in zebrafish embryos and larvae dealt with atrazine (ATR) at different concentrations (0.0001, 0.001, 0.01, 0.1, and 1 mg/L).
This study showed that the development of the sarcomere and the arrangement of white muscle myofibers were affected by ATR significantly and the length of sarcomere shortened.
Further analysis of the results showed that the AChE activity in juvenile fish which was treated with ATR was downregulated, which can indicate that the innervation efficiency to the muscle was impaired.
Conversely, the AChE activity in zebrafish embryos which was treated with ATR was upregulated.
A parallel phenomenon showed that embryonic primary sensory neurons (Rohon-Beard cells), principally expressing AChE in embryos, survived the physiological apoptosis.
These phenomena demonstrated that the motor integration ability of the zebrafish was damaged by ATR which can disturb the development of sensory neurons and sarcomere and the innervations of muscle.
American Psychological Association (APA)
Wang, Hao& Mu, Shumei& Zhang, Fengjuan& Wang, Hailing& Liu, Huan& Zhang, Han…[et al.]. 2015. Effects of Atrazine on the Development of Neural System of Zebrafish, Danio rerio. BioMed Research International،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1057460
Modern Language Association (MLA)
Wang, Hao…[et al.]. Effects of Atrazine on the Development of Neural System of Zebrafish, Danio rerio. BioMed Research International No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1057460
American Medical Association (AMA)
Wang, Hao& Mu, Shumei& Zhang, Fengjuan& Wang, Hailing& Liu, Huan& Zhang, Han…[et al.]. Effects of Atrazine on the Development of Neural System of Zebrafish, Danio rerio. BioMed Research International. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1057460
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1057460