Screening Mild and Major Neurocognitive Disorders in Parkinson’s Disease
Joint Authors
Karádi, Kázmér
Kovács, Norbert
Lucza, Tivadar
Kállai, János
Weintraut, Rita
Janszky, József
Makkos, Attila
Komoly, Sámuel
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-05-19
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Introduction.
Among the nonmotor features of Parkinson’s disease (PD), cognitive impairment is one of the most troublesome problems.
New diagnostic criteria for mild and major neurocognitive disorder (NCD) in PD were established by Diagnostic and Statistical Manual of Mental Disorders 5th edition (DSM-5).
The aim of our study was to establish the diagnostic accuracy of widely used screening tests for NCD in PD.
Methods.
Within the scope of our study we evaluated the sensitivity and specificity of different neuropsychological tests (Addenbrooke’s Cognitive Examination (ACE), Mattis Dementia Rating Scale (MDRS), Mini Mental StateExamination (MMSE), and Montreal Cognitive Assessment (MoCA)) in 370 PD patients without depression.
Results.
MoCA and ACE feature the finest diagnostic accuracy for detecting mild cognitive disorder in PD (DSM-5) at the cut-off scores of 23.5 and 83.5 points, respectively.
The diagnostic accuracy of these tests was 0.859 (95% CI: 0.818–0.894, MoCA) and 0.820 (95% CI: 0.774–0.859, ACE).
In the detection of major NCD (DSM-5), MoCA and MDRS tests exhibited the best diagnostic accuracy at the cut-off scores of 20.5 and 132.5 points, respectively.
The diagnostic accuracy of these tests was 0.863 (95% CI: 0.823–0.897, MoCA) and 0.830 (95% CI: 0.785–0.869, MDRS).
Conclusion.
Our study demonstrated that the MoCA may be the most suitable test for detecting mild and major NCD in PD.
American Psychological Association (APA)
Lucza, Tivadar& Karádi, Kázmér& Kállai, János& Weintraut, Rita& Janszky, József& Makkos, Attila…[et al.]. 2015. Screening Mild and Major Neurocognitive Disorders in Parkinson’s Disease. Behavioural Neurology،Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1057601
Modern Language Association (MLA)
Lucza, Tivadar…[et al.]. Screening Mild and Major Neurocognitive Disorders in Parkinson’s Disease. Behavioural Neurology No. 2015 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1057601
American Medical Association (AMA)
Lucza, Tivadar& Karádi, Kázmér& Kállai, János& Weintraut, Rita& Janszky, József& Makkos, Attila…[et al.]. Screening Mild and Major Neurocognitive Disorders in Parkinson’s Disease. Behavioural Neurology. 2015. Vol. 2015, no. 2015, pp.1-10.
https://search.emarefa.net/detail/BIM-1057601
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1057601