Incidence and Risk Factors for Delirium among Mechanically Ventilated Patients in an African Intensive Care Setting: An Observational Multicenter Study
Joint Authors
Kwizera, Arthur
Nakibuuka, Jane
Ssemogerere, Lameck
Sendikadiwa, Charles
Obua, Daniel
Kizito, Samuel
Tumukunde, Janat
Wabule, Agnes
Nakasujja, Noeline
Source
Critical Care Research and Practice
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-04-05
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Aim.
Delirium is common among mechanically ventilated patients in the intensive care unit (ICU).
There are little data regarding delirium among mechanically ventilated patients in Africa.
We sought to determine the burden of delirium and associated factors in Uganda.
Methods.
We conducted a multicenter prospective study among mechanically ventilated patients in Uganda.
Eligible patients were screened daily for delirium using the confusional assessment method (CAM-ICU).
Comparisons were made using t-test, chi-squares, and Fisher’s exact test.
Predictors were assessed using logistic regression.
The level of statistical significance was set at P<0.05.
Results.
Of 160 patients, 81 (51%) had delirium.
Median time to onset of delirium was 3.7 days.
At bivariate analysis, history of mental illness, sedation, multiorgan dysfunction, neurosurgery, tachypnea, low mean arterial pressure, oliguria, fevers, metabolic acidosis, respiratory acidosis, anaemia, physical restraints, marital status, and endotracheal tube use were significant predictors.
At multivariable analysis, having a history of mental illness, sedation, respiratory acidosis, higher PEEP, endotracheal tubes, and anaemia predicted delirium.
Conclusion.
The prevalence of delirium in a young African population is lower than expected considering the high mortality.
A history of mental illness, anaemia, sedation, endotracheal tube use, and respiratory acidosis were factors associated with delirium.
American Psychological Association (APA)
Kwizera, Arthur& Nakibuuka, Jane& Ssemogerere, Lameck& Sendikadiwa, Charles& Obua, Daniel& Kizito, Samuel…[et al.]. 2015. Incidence and Risk Factors for Delirium among Mechanically Ventilated Patients in an African Intensive Care Setting: An Observational Multicenter Study. Critical Care Research and Practice،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1057637
Modern Language Association (MLA)
Kwizera, Arthur…[et al.]. Incidence and Risk Factors for Delirium among Mechanically Ventilated Patients in an African Intensive Care Setting: An Observational Multicenter Study. Critical Care Research and Practice No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1057637
American Medical Association (AMA)
Kwizera, Arthur& Nakibuuka, Jane& Ssemogerere, Lameck& Sendikadiwa, Charles& Obua, Daniel& Kizito, Samuel…[et al.]. Incidence and Risk Factors for Delirium among Mechanically Ventilated Patients in an African Intensive Care Setting: An Observational Multicenter Study. Critical Care Research and Practice. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1057637
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1057637