The Use of Sodium Bicarbonate in the Treatment of Acidosis in Sepsis: A Literature Update on a Long Term Debate

Joint Authors

Karanikolas, Menelaos
Velissaris, Dimitrios
Karamouzos, Vasilios
Ktenopoulos, Nikolaos
Pierrakos, Charalampos

Source

Critical Care Research and Practice

Issue

Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2015-07-30

Country of Publication

Egypt

No. of Pages

7

Main Subjects

Medicine

Abstract EN

Introduction.

Sepsis and its consequences such as metabolic acidosis are resulting in increased mortality.

Although correction of metabolic acidosis with sodium bicarbonate seems a reasonable approach, there is ongoing debate regarding the role of bicarbonates as a therapeutic option.

Methods.

We conducted a PubMed literature search in order to identify published literature related to the effects of sodium bicarbonate treatment on metabolic acidosis due to sepsis.

The search included all articles published in English in the last 35 years.

Results.

There is ongoing debate regarding the use of bicarbonates for the treatment of acidosis in sepsis, but there is a trend towards not using bicarbonate in sepsis patients with arterial blood gas pH>7.15.

Conclusions.

Routine use of bicarbonate for treatment of severe acidemia and lactic acidosis due to sepsis is subject of controversy, and current opinion does not favor routine use of bicarbonates.

However, available evidence is inconclusive, and more studies are required to determine the potential benefit, if any, of bicarbonate therapy in the sepsis patient with acidosis.

American Psychological Association (APA)

Velissaris, Dimitrios& Karamouzos, Vasilios& Ktenopoulos, Nikolaos& Pierrakos, Charalampos& Karanikolas, Menelaos. 2015. The Use of Sodium Bicarbonate in the Treatment of Acidosis in Sepsis: A Literature Update on a Long Term Debate. Critical Care Research and Practice،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1057639

Modern Language Association (MLA)

Velissaris, Dimitrios…[et al.]. The Use of Sodium Bicarbonate in the Treatment of Acidosis in Sepsis: A Literature Update on a Long Term Debate. Critical Care Research and Practice No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1057639

American Medical Association (AMA)

Velissaris, Dimitrios& Karamouzos, Vasilios& Ktenopoulos, Nikolaos& Pierrakos, Charalampos& Karanikolas, Menelaos. The Use of Sodium Bicarbonate in the Treatment of Acidosis in Sepsis: A Literature Update on a Long Term Debate. Critical Care Research and Practice. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1057639

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1057639