The Use of Sodium Bicarbonate in the Treatment of Acidosis in Sepsis: A Literature Update on a Long Term Debate
Joint Authors
Karanikolas, Menelaos
Velissaris, Dimitrios
Karamouzos, Vasilios
Ktenopoulos, Nikolaos
Pierrakos, Charalampos
Source
Critical Care Research and Practice
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-07-30
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Introduction.
Sepsis and its consequences such as metabolic acidosis are resulting in increased mortality.
Although correction of metabolic acidosis with sodium bicarbonate seems a reasonable approach, there is ongoing debate regarding the role of bicarbonates as a therapeutic option.
Methods.
We conducted a PubMed literature search in order to identify published literature related to the effects of sodium bicarbonate treatment on metabolic acidosis due to sepsis.
The search included all articles published in English in the last 35 years.
Results.
There is ongoing debate regarding the use of bicarbonates for the treatment of acidosis in sepsis, but there is a trend towards not using bicarbonate in sepsis patients with arterial blood gas pH>7.15.
Conclusions.
Routine use of bicarbonate for treatment of severe acidemia and lactic acidosis due to sepsis is subject of controversy, and current opinion does not favor routine use of bicarbonates.
However, available evidence is inconclusive, and more studies are required to determine the potential benefit, if any, of bicarbonate therapy in the sepsis patient with acidosis.
American Psychological Association (APA)
Velissaris, Dimitrios& Karamouzos, Vasilios& Ktenopoulos, Nikolaos& Pierrakos, Charalampos& Karanikolas, Menelaos. 2015. The Use of Sodium Bicarbonate in the Treatment of Acidosis in Sepsis: A Literature Update on a Long Term Debate. Critical Care Research and Practice،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1057639
Modern Language Association (MLA)
Velissaris, Dimitrios…[et al.]. The Use of Sodium Bicarbonate in the Treatment of Acidosis in Sepsis: A Literature Update on a Long Term Debate. Critical Care Research and Practice No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1057639
American Medical Association (AMA)
Velissaris, Dimitrios& Karamouzos, Vasilios& Ktenopoulos, Nikolaos& Pierrakos, Charalampos& Karanikolas, Menelaos. The Use of Sodium Bicarbonate in the Treatment of Acidosis in Sepsis: A Literature Update on a Long Term Debate. Critical Care Research and Practice. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1057639
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1057639