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Diagnosis of Lung Cancer by Fractal Analysis of Damaged DNA
Joint Authors
Namazi, Hamidreza
Kiminezhadmalaie, Mona
Source
Computational and Mathematical Methods in Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-11
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Cancer starts when cells in a part of the body start to grow out of control.
In fact cells become cancer cells because of DNA damage.
A DNA walk of a genome represents how the frequency of each nucleotide of a pairing nucleotide couple changes locally.
In this research in order to study the cancer genes, DNA walk plots of genomes of patients with lung cancer were generated using a program written in MATLAB language.
The data so obtained was checked for fractal property by computing the fractal dimension using a program written in MATLAB.
Also, the correlation of damaged DNA was studied using the Hurst exponent measure.
We have found that the damaged DNA sequences are exhibiting higher degree of fractality and less correlation compared with normal DNA sequences.
So we confirmed this method can be used for early detection of lung cancer.
The method introduced in this research not only is useful for diagnosis of lung cancer but also can be applied for detection and growth analysis of different types of cancers.
American Psychological Association (APA)
Namazi, Hamidreza& Kiminezhadmalaie, Mona. 2015. Diagnosis of Lung Cancer by Fractal Analysis of Damaged DNA. Computational and Mathematical Methods in Medicine،Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1057838
Modern Language Association (MLA)
Namazi, Hamidreza& Kiminezhadmalaie, Mona. Diagnosis of Lung Cancer by Fractal Analysis of Damaged DNA. Computational and Mathematical Methods in Medicine No. 2015 (2015), pp.1-11.
https://search.emarefa.net/detail/BIM-1057838
American Medical Association (AMA)
Namazi, Hamidreza& Kiminezhadmalaie, Mona. Diagnosis of Lung Cancer by Fractal Analysis of Damaged DNA. Computational and Mathematical Methods in Medicine. 2015. Vol. 2015, no. 2015, pp.1-11.
https://search.emarefa.net/detail/BIM-1057838
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1057838