Time-Delayed Models of Gene Regulatory Networks
Joint Authors
Blyuss, Konstantin
Parmar, K.
Kyrychko, Y. N.
Hogan, S. J.
Source
Computational and Mathematical Methods in Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-20
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Abstract EN
We discuss different mathematical models of gene regulatory networks as relevant to the onset and development of cancer.
After discussion of alternative modelling approaches, we use a paradigmatic two-gene network to focus on the role played by time delays in the dynamics of gene regulatory networks.
We contrast the dynamics of the reduced model arising in the limit of fast mRNA dynamics with that of the full model.
The review concludes with the discussion of some open problems.
American Psychological Association (APA)
Parmar, K.& Blyuss, Konstantin& Kyrychko, Y. N.& Hogan, S. J.. 2015. Time-Delayed Models of Gene Regulatory Networks. Computational and Mathematical Methods in Medicine،Vol. 2015, no. 2015, pp.1-16.
https://search.emarefa.net/detail/BIM-1057868
Modern Language Association (MLA)
Parmar, K.…[et al.]. Time-Delayed Models of Gene Regulatory Networks. Computational and Mathematical Methods in Medicine No. 2015 (2015), pp.1-16.
https://search.emarefa.net/detail/BIM-1057868
American Medical Association (AMA)
Parmar, K.& Blyuss, Konstantin& Kyrychko, Y. N.& Hogan, S. J.. Time-Delayed Models of Gene Regulatory Networks. Computational and Mathematical Methods in Medicine. 2015. Vol. 2015, no. 2015, pp.1-16.
https://search.emarefa.net/detail/BIM-1057868
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1057868
