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Parameter Optimization for Selected Correlation Analysis of Intracranial Pathophysiology
Joint Authors
Faltermeier, Rupert
Proescholdt, Martin A.
Brawanski, Alexander
Bele, S.
Source
Computational and Mathematical Methods in Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-11-29
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Recently we proposed a mathematical tool set, called selected correlation analysis, that reliably detects positive and negative correlations between arterial blood pressure (ABP) and intracranial pressure (ICP).
Such correlations are associated with severe impairment of the cerebral autoregulation and intracranial compliance, as predicted by a mathematical model.
The time resolved selected correlation analysis is based on a windowing technique combined with Fourier-based coherence calculations and therefore depends on several parameters.
For real time application of this method at an ICU it is inevitable to adjust this mathematical tool for high sensitivity and distinct reliability.
In this study, we will introduce a method to optimize the parameters of the selected correlation analysis by correlating an index, called selected correlation positive (SCP), with the outcome of the patients represented by the Glasgow Outcome Scale (GOS).
For that purpose, the data of twenty-five patients were used to calculate the SCP value for each patient and multitude of feasible parameter sets of the selected correlation analysis.
It could be shown that an optimized set of parameters is able to improve the sensitivity of the method by a factor greater than four in comparison to our first analyses.
American Psychological Association (APA)
Faltermeier, Rupert& Proescholdt, Martin A.& Bele, S.& Brawanski, Alexander. 2015. Parameter Optimization for Selected Correlation Analysis of Intracranial Pathophysiology. Computational and Mathematical Methods in Medicine،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1057961
Modern Language Association (MLA)
Faltermeier, Rupert…[et al.]. Parameter Optimization for Selected Correlation Analysis of Intracranial Pathophysiology. Computational and Mathematical Methods in Medicine No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1057961
American Medical Association (AMA)
Faltermeier, Rupert& Proescholdt, Martin A.& Bele, S.& Brawanski, Alexander. Parameter Optimization for Selected Correlation Analysis of Intracranial Pathophysiology. Computational and Mathematical Methods in Medicine. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1057961
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1057961