Recurrent Febrile Neutropenia and Thrombocytopenia in a Chronic Cocaine User: A Case of Levamisole Induced Complications

Abstract EN

Cocaine is used by approximately 1.5 million Americans each month and up to 69% of the cocaine seized contains levamisole.

The real incidence of cocaine-levamisole induced neutropenia is unclear but probably underestimated.

Associated complications include fever, thrombocytopenia, skin-vasculitis disorders, and rarely kidney injury.

We present a young male, with chronic active cocaine use presenting with recurrent episodes of febrile neutropenia and thrombocytopenia.

He underwent extensive work-up and was treated with many antibiotics and we suspect that his neutropenia and thrombocytopenia were caused by recurrent cocaine-levamisole use.