A Rare Case of Melanosis of the Hard Palate Mucosa in a Patient with Chronic Myeloid Leukemia
Joint Authors
Fantozzi, Paolo Junior
Bosco, Daniela
Palaia, Gaspare
Umberto, Romeo
Gianluca, Tenore
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-09-15
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Imatinib Mesylate, also known as Gleevec or ST1-571, is a tyrosine-kinase inhibitor used as the gold standard medication for the chronic myeloid leukemia (CML); Imatinib has indeed deeply revolutionized the CML therapy allowing most patients to have a good quality of life.
Despite its beneficial effects, Imatinib has significant side effects such as mucosal pigmentation.
A 72-year-old female having an Imatinib induced mucosal pigmentation is presented: she has been treated with Imatinib since 2003 and only in 2014 discovered, during a routine dental visit, having a pigmented lesion on her hard palate mucosa.
Histopathologically, the lesion shows the deposition of fine dark brown spherical bodies within the lamina propria and cloaked in between the collagen fibers.
There was no sign of inflammation, hyperplasia, or hemorrhage in the tissue.
American Psychological Association (APA)
Umberto, Romeo& Palaia, Gaspare& Fantozzi, Paolo Junior& Gianluca, Tenore& Bosco, Daniela. 2015. A Rare Case of Melanosis of the Hard Palate Mucosa in a Patient with Chronic Myeloid Leukemia. Case Reports in Dentistry،Vol. 2015, no. 2015, pp.1-3.
https://search.emarefa.net/detail/BIM-1058326
Modern Language Association (MLA)
Umberto, Romeo…[et al.]. A Rare Case of Melanosis of the Hard Palate Mucosa in a Patient with Chronic Myeloid Leukemia. Case Reports in Dentistry No. 2015 (2015), pp.1-3.
https://search.emarefa.net/detail/BIM-1058326
American Medical Association (AMA)
Umberto, Romeo& Palaia, Gaspare& Fantozzi, Paolo Junior& Gianluca, Tenore& Bosco, Daniela. A Rare Case of Melanosis of the Hard Palate Mucosa in a Patient with Chronic Myeloid Leukemia. Case Reports in Dentistry. 2015. Vol. 2015, no. 2015, pp.1-3.
https://search.emarefa.net/detail/BIM-1058326
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1058326