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Multiple Congenital Granular Cell Epulis: Case Report and Immunohistochemical Profile with Emphasis on Vascularization
Joint Authors
Bianchi, Patricia Roccon
Ribeiro, José Wagner Banterli
Passador Santos, Fabricio
Soares, Andresa Borges
Soares de Araujo, Ney
de Araújo, Vera Cavalcanti
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-02-05
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Congenital granular cell epulis is a rare benign soft tissue lesion arising from the alveolar ridge in neonates.
A rare case of multiple congenital granular cell epulis is reported, alongside a description of its vascular immunohistochemical profile.
A female newborn presented with two exophytic pedunculated red nodules located on the alveolar ridge between the future eruption sites of the incisors and canines of the mandible and maxilla.
A conservative surgical excision was performed on the second day of life.
Histology revealed proliferation of round granular cells containing an abundant eosinophilic cytoplasm with basophilic nuclei, ranging from round to oval in shape.
Numerous blood vessels were also seen.
Immunohistochemical analysis of the granular cells revealed positivity for CD68, D2-40, Ki67, VEGF, and FGF and negativity for S100, CD34, and CD105.
Immunostaining for CD34, CD105, and D2-40 confirmed the presence of a large number of blood and lymphatic vessels.
Although rare, an understanding of this lesion is paramount for correct diagnosis and appropriate treatment.
In the present report, the immunohistochemical profile confirmed increased vascularization, proving that these lesions are composed of not only new and preexisting blood vessels, but also lymphatic vessels.
American Psychological Association (APA)
Bianchi, Patricia Roccon& de Araújo, Vera Cavalcanti& Ribeiro, José Wagner Banterli& Passador Santos, Fabricio& Soares de Araujo, Ney& Soares, Andresa Borges. 2015. Multiple Congenital Granular Cell Epulis: Case Report and Immunohistochemical Profile with Emphasis on Vascularization. Case Reports in Dentistry،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1058338
Modern Language Association (MLA)
Bianchi, Patricia Roccon…[et al.]. Multiple Congenital Granular Cell Epulis: Case Report and Immunohistochemical Profile with Emphasis on Vascularization. Case Reports in Dentistry No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1058338
American Medical Association (AMA)
Bianchi, Patricia Roccon& de Araújo, Vera Cavalcanti& Ribeiro, José Wagner Banterli& Passador Santos, Fabricio& Soares de Araujo, Ney& Soares, Andresa Borges. Multiple Congenital Granular Cell Epulis: Case Report and Immunohistochemical Profile with Emphasis on Vascularization. Case Reports in Dentistry. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1058338
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1058338