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Nonclassical Congenital Adrenal Hyperplasia and Pregnancy
Joint Authors
Aydin, Cevdet
Cuhaci, Neslihan
Ersoy, Reyhan
Cakir, Bekir
Pınarlı, Ferda Alpaslan
Yesilyurt, Ahmet
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-08
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Objective.
The most common form of congenital adrenal hyperplasia (CAH) is 21-hydroxylase (21-OH) deficiency due to mutation of the CYP21A2 gene.
Patients with nonclassical CAH (NC-CAH) are usually asymptomatic at birth and typically present in late childhood, adolescence, or adulthood with symptoms of excessive androgen secretion.
Subfertility is relative in NC-CAH, but the incidence of spontaneous miscarriage is higher.
Here, we report a previously undiagnosed female who gave birth to a normal male child and is planning to become pregnant again.
Case Report.
A 32-year-old female was referred to our clinic for obesity.
Her medical history revealed that she had had three pregnancies.
She was planning to become pregnant again.
Her laboratory results revealed that she had NC-CAH.
Since her husband is the son of her aunt and she had miscarriages and intrauterin exitus in her history, their genetic analyses were performed.
Conclusion.
Since most patients with NC-CAH have a severe mutation, these patients may give birth to a child with the classical CAH (C-CAH) if their partner is also carrying a severe mutation.
Females with NC-CAH who desire pregnancy must be aware of the risk of having an infant with C-CAH.
American Psychological Association (APA)
Cuhaci, Neslihan& Aydin, Cevdet& Yesilyurt, Ahmet& Pınarlı, Ferda Alpaslan& Ersoy, Reyhan& Cakir, Bekir. 2015. Nonclassical Congenital Adrenal Hyperplasia and Pregnancy. Case Reports in Endocrinology،Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1058398
Modern Language Association (MLA)
Cuhaci, Neslihan…[et al.]. Nonclassical Congenital Adrenal Hyperplasia and Pregnancy. Case Reports in Endocrinology No. 2015 (2015), pp.1-4.
https://search.emarefa.net/detail/BIM-1058398
American Medical Association (AMA)
Cuhaci, Neslihan& Aydin, Cevdet& Yesilyurt, Ahmet& Pınarlı, Ferda Alpaslan& Ersoy, Reyhan& Cakir, Bekir. Nonclassical Congenital Adrenal Hyperplasia and Pregnancy. Case Reports in Endocrinology. 2015. Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1058398
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1058398