A Rare Presentation of Transfusional Hemochromatosis: Hypogonadotropic Hypogonadism

Joint Authors

Atmaca, Murat
Üçler, Rıfkı
Alay, Murat
Dirik, Yaren
Bora, Aydın
Kara, Erdal
Olmez, Sehmus

Source

Case Reports in Endocrinology

Issue

Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-4, 4 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2015-07-21

Country of Publication

Egypt

No. of Pages

4

Main Subjects

Diseases

Abstract EN

Hemochromatosis is a disease caused by extraordinary iron deposition in parenchymal cells leading to cellular damage and organ dysfunction.

β-thalassemia major is one of the causes of secondary hemochromatosis due to regular transfusional treatment for maintaining adequate levels of hemoglobin.

Hypogonadism is one of the potential complications of hemochromatosis, usually seen in patients with a severe iron overload, and it shows an association with diabetes and cirrhosis in adult patients.

We describe a patient with mild transfusional hemochromatosis due to β-thalassemia major, presenting with central hypogonadism in the absence of cirrhosis or diabetes.

Our case showed an atypical presentation with hypogonadotropic hypogonadism without severe hyperferritinemia, cirrhosis, or diabetes.

With this case, we aim to raise awareness of hypogonadotropic hypogonadism in patients with intensive transfused thalassemia major even if not severe hemochromatosis so that hypogonadism related complications, such as osteoporosis, anergia, weakness, sexual dysfunction, and infertility, could be more effectively managed in these patients.

American Psychological Association (APA)

Üçler, Rıfkı& Kara, Erdal& Atmaca, Murat& Olmez, Sehmus& Alay, Murat& Dirik, Yaren…[et al.]. 2015. A Rare Presentation of Transfusional Hemochromatosis: Hypogonadotropic Hypogonadism. Case Reports in Endocrinology،Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1058404

Modern Language Association (MLA)

Üçler, Rıfkı…[et al.]. A Rare Presentation of Transfusional Hemochromatosis: Hypogonadotropic Hypogonadism. Case Reports in Endocrinology No. 2015 (2015), pp.1-4.
https://search.emarefa.net/detail/BIM-1058404

American Medical Association (AMA)

Üçler, Rıfkı& Kara, Erdal& Atmaca, Murat& Olmez, Sehmus& Alay, Murat& Dirik, Yaren…[et al.]. A Rare Presentation of Transfusional Hemochromatosis: Hypogonadotropic Hypogonadism. Case Reports in Endocrinology. 2015. Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1058404

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1058404