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Antineutrophilic Cytoplasmic Antibody Positive VasculitisAssociated with Methimazole Use
Joint Authors
Shikha, Deep
Harris, Jonathan
Park, Patricia
Resta, Christine A.
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-04-28
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
ANCA-associated vasculitis (AAV) is a rare and potentially life threatening complication associated with antithyroid drug use.
It is more commonly reported with propylthiouracil, with fewer cases reported with methimazole use.
We present the case of a 55-year-old man with toxic multinodular goiter which was treated with methimazole for 6 months.
He developed ANCA positive leukocytoclastic vasculitis with hemorrhagic and necrotic bullous lesions of lower extremities.
The vasculitis was initially thought to be secondary to recent cephalosporin use; however, the skin lesions progressed despite stopping the cephalosporin and treatment with steroids, and he developed osteomyelitis.
His vasculitis resolved after cessation of methimazole use.
This case highlights the importance of careful monitoring for variable manifestations of AAV in patients treated with methimazole.
American Psychological Association (APA)
Shikha, Deep& Harris, Jonathan& Resta, Christine A.& Park, Patricia. 2015. Antineutrophilic Cytoplasmic Antibody Positive VasculitisAssociated with Methimazole Use. Case Reports in Endocrinology،Vol. 2015, no. 2015, pp.1-3.
https://search.emarefa.net/detail/BIM-1058406
Modern Language Association (MLA)
Shikha, Deep…[et al.]. Antineutrophilic Cytoplasmic Antibody Positive VasculitisAssociated with Methimazole Use. Case Reports in Endocrinology No. 2015 (2015), pp.1-3.
https://search.emarefa.net/detail/BIM-1058406
American Medical Association (AMA)
Shikha, Deep& Harris, Jonathan& Resta, Christine A.& Park, Patricia. Antineutrophilic Cytoplasmic Antibody Positive VasculitisAssociated with Methimazole Use. Case Reports in Endocrinology. 2015. Vol. 2015, no. 2015, pp.1-3.
https://search.emarefa.net/detail/BIM-1058406
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1058406