Characteristics and Treatment Results of 5 Patients with Fibrous Dysplasia and Review of the Literature
Joint Authors
Ozdemir Kutbay, Nilufer
Sarer Yurekli, Banu
Kartal Baykan, Emine
Saygili, Fusun
Sahin, Serap Baydur
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-06-14
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Aim.
Fibrous dysplasia is a rare bone disease caused by missense mutation leading to abnormal fibroblast and osteoblast proliferation and increased bone resorption.
FD can present in monostotic or polyostotic forms.
About 3% of FD could be in association with McCune-Albright syndrome (MAS).
Because FD is a rare disease, there is limited data in the literature about characteristics of disease and response to treatment.
Methods.
We present our five cases of FD with general properties and their responses to medical treatment.
Results.
Two of our patients had polyostotic and three had monostotic FD.
One of the polyostotic patients had MAS.
One of our patients had surgery for femur fractures, facial asymmetry, and findings of compression.
Four patients were given pamidronate; one was given zoledronic acid as bisphosphonate treatment.
Bone pain was relieved in all patients with medical treatment.
Conclusion.
There was a decrease in bone turnover markers to some degree with medical treatment but no radiological improvement was observed.
American Psychological Association (APA)
Ozdemir Kutbay, Nilufer& Sarer Yurekli, Banu& Kartal Baykan, Emine& Sahin, Serap Baydur& Saygili, Fusun. 2015. Characteristics and Treatment Results of 5 Patients with Fibrous Dysplasia and Review of the Literature. Case Reports in Endocrinology،Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1058411
Modern Language Association (MLA)
Ozdemir Kutbay, Nilufer…[et al.]. Characteristics and Treatment Results of 5 Patients with Fibrous Dysplasia and Review of the Literature. Case Reports in Endocrinology No. 2015 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1058411
American Medical Association (AMA)
Ozdemir Kutbay, Nilufer& Sarer Yurekli, Banu& Kartal Baykan, Emine& Sahin, Serap Baydur& Saygili, Fusun. Characteristics and Treatment Results of 5 Patients with Fibrous Dysplasia and Review of the Literature. Case Reports in Endocrinology. 2015. Vol. 2015, no. 2015, pp.1-7.
https://search.emarefa.net/detail/BIM-1058411
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1058411