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Methimazole Associated Neutropenia in a Preterm Neonate Treated for Hyperthyroidism
Joint Authors
Kubicky, Rita Ann
Angelis, Dimitrios
Zubrow, Alan B.
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-02-24
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Maternal Graves’ disease is relatively uncommon with an estimated incidence of 0.4%–1% of all pregnancies, but only 1–5% of newborns delivered to mothers with Graves’ disease develop overt clinical signs and symptoms of hyperthyroidism.
Here, we describe a case of a 1380-gram female neonate who was born at 30-week gestation to a mother with Graves’ disease.
Our patient presented with hyperthyroidism followed by transient hypothyroidism requiring treatment with levothyroxine.
While hyperthyroid, she was treated with methimazole, iodine, and a beta-blocker.
20 days after the initiation of methimazole, she developed neutropenia.
The neutrophil counts started to improve immediately after the initiation of the weaning of methimazole.
To the best of our knowledge, this is the first case reported in the literature of methimazole induced neutropenia in a preterm infant being treated for neonatal Graves’ disease.
American Psychological Association (APA)
Angelis, Dimitrios& Kubicky, Rita Ann& Zubrow, Alan B.. 2015. Methimazole Associated Neutropenia in a Preterm Neonate Treated for Hyperthyroidism. Case Reports in Endocrinology،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1058413
Modern Language Association (MLA)
Angelis, Dimitrios…[et al.]. Methimazole Associated Neutropenia in a Preterm Neonate Treated for Hyperthyroidism. Case Reports in Endocrinology No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1058413
American Medical Association (AMA)
Angelis, Dimitrios& Kubicky, Rita Ann& Zubrow, Alan B.. Methimazole Associated Neutropenia in a Preterm Neonate Treated for Hyperthyroidism. Case Reports in Endocrinology. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1058413
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1058413