Measurement of Serum Free Thyroxine Index May Provide Additional Case Detection Compared to Free Thyroxine in the Diagnosis of Central Hypothyroidism
Joint Authors
Hamrahian, Amir
Hatipoglu, Betul
Pantalone, Kevin M.
Gupta, Manjula K.
Kennedy, Laurence
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-12-08
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
The diagnosis of central hypothyroidism is often suspected in patients with hypothalamic/pituitary pathology, in the setting of low, normal, or even slightly elevated serum TSH and low free thyroxine (FT4).
We present four cases of central hypothyroidism (three had known pituitary pathology) in whom central hypothyroidism was diagnosed after the serum free thyroxine index (FTI) was found to be low.
All had normal range serum TSH and free thyroxine levels.
This report illustrates that the assessment of the serum FTI may be helpful in making the diagnosis of central hypothyroidism in the appropriate clinical setting and when free T4 is in the low-normal range, particularly in patients with multiple anterior pituitary hormone deficiencies and/or with symptoms suggestive of hypothyroidism.
American Psychological Association (APA)
Pantalone, Kevin M.& Hatipoglu, Betul& Gupta, Manjula K.& Kennedy, Laurence& Hamrahian, Amir. 2015. Measurement of Serum Free Thyroxine Index May Provide Additional Case Detection Compared to Free Thyroxine in the Diagnosis of Central Hypothyroidism. Case Reports in Endocrinology،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1058434
Modern Language Association (MLA)
Pantalone, Kevin M.…[et al.]. Measurement of Serum Free Thyroxine Index May Provide Additional Case Detection Compared to Free Thyroxine in the Diagnosis of Central Hypothyroidism. Case Reports in Endocrinology No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1058434
American Medical Association (AMA)
Pantalone, Kevin M.& Hatipoglu, Betul& Gupta, Manjula K.& Kennedy, Laurence& Hamrahian, Amir. Measurement of Serum Free Thyroxine Index May Provide Additional Case Detection Compared to Free Thyroxine in the Diagnosis of Central Hypothyroidism. Case Reports in Endocrinology. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1058434
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1058434