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Development of Agranulocytosis after Discontinuation of Methimazole: An Unusual Case
Joint Authors
Atmaca, Murat
Üçler, Rıfkı
Alay, Murat
Kara, Erdal
Candar, Ömer
Göy, Burhan
Turan, Mahfuz
Demir, Yusuf
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-08-03
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Agranulocytosis is a rare and critical adverse effect of antithyroid drugs (ATD).
The occurrence of agranulocytosis in continuous ATD treatment patients is well known; however, a case of ATD agranulocytosis occurring following the discontinuation of methimazole (MMI) treatment is not a usual situation.
We herein describe a case of a 41-year-old woman who was previously administered methimazole (MMI) for ten days and developed ATD-induced agranulocytosis and symptoms of an upper respiratory tract infection after three weeks following discontinuation of MMI treatment.
A thorough hematologic and serological evaluation did not disclose an alternative cause for the agranulocytosis.
After receiving empirical antibiotic treatment, she responded successfully with clinical improvement of her symptoms and resolved neutropenia on the seventh day.
This case is atypical because agranulocytosis developed after discontinuation of MMI, which strengthens the importance of remaining alert for signs of agranulocytosis even after discontinuation of ATD treatment.
American Psychological Association (APA)
Üçler, Rıfkı& Atmaca, Murat& Candar, Ömer& Alay, Murat& Göy, Burhan& Kara, Erdal…[et al.]. 2015. Development of Agranulocytosis after Discontinuation of Methimazole: An Unusual Case. Case Reports in Endocrinology،Vol. 2015, no. 2015, pp.1-3.
https://search.emarefa.net/detail/BIM-1058435
Modern Language Association (MLA)
Üçler, Rıfkı…[et al.]. Development of Agranulocytosis after Discontinuation of Methimazole: An Unusual Case. Case Reports in Endocrinology No. 2015 (2015), pp.1-3.
https://search.emarefa.net/detail/BIM-1058435
American Medical Association (AMA)
Üçler, Rıfkı& Atmaca, Murat& Candar, Ömer& Alay, Murat& Göy, Burhan& Kara, Erdal…[et al.]. Development of Agranulocytosis after Discontinuation of Methimazole: An Unusual Case. Case Reports in Endocrinology. 2015. Vol. 2015, no. 2015, pp.1-3.
https://search.emarefa.net/detail/BIM-1058435
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1058435