Recurrent C. difficile in a Patient with IgG Deficiency

Joint Authors

Jehangir, Asad
Bennett, Kyle
Fareedy, Shoaib Bilal
Rettew, Andrew
Shaikh, Bilal
Qureshi, Anam
Jehangir, Qasim
Alweis, Richard

Source

Case Reports in Gastrointestinal Medicine

Issue

Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-3, 3 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2015-04-05

Country of Publication

Egypt

No. of Pages

3

Main Subjects

Diseases

Abstract EN

IgG deficiency can predispose to recurrent pyogenic infections.

The association of IgG deficiency with Clostridium difficile infection has been infrequently reported in the literature.

We present a case of a middle-age woman with multiple hospitalizations for recurrent C.

difficile in a short span of time which prompted consideration of a possible fecal transplant.

On evaluation, she was found to have low total IgG, with subclass analysis revealing low IgG1 and IgG3.

She was started on monthly infusions of immunoglobulins and one year after her last episode of C.

difficile she has not had any recurrence.

The role of immunoglobulin infusion in the treatment of recurrent C.

difficile is controversial, with some studies revealing no clear evidence of benefit.

Our case report suggests that the patients who have underlying IgG deficiency may benefit from immunoglobulin, as this can significantly reduce the incidence of recurrent infections and hence save the healthcare costs.

American Psychological Association (APA)

Jehangir, Asad& Bennett, Kyle& Fareedy, Shoaib Bilal& Rettew, Andrew& Shaikh, Bilal& Qureshi, Anam…[et al.]. 2015. Recurrent C. difficile in a Patient with IgG Deficiency. Case Reports in Gastrointestinal Medicine،Vol. 2015, no. 2015, pp.1-3.
https://search.emarefa.net/detail/BIM-1058536

Modern Language Association (MLA)

Jehangir, Asad…[et al.]. Recurrent C. difficile in a Patient with IgG Deficiency. Case Reports in Gastrointestinal Medicine No. 2015 (2015), pp.1-3.
https://search.emarefa.net/detail/BIM-1058536

American Medical Association (AMA)

Jehangir, Asad& Bennett, Kyle& Fareedy, Shoaib Bilal& Rettew, Andrew& Shaikh, Bilal& Qureshi, Anam…[et al.]. Recurrent C. difficile in a Patient with IgG Deficiency. Case Reports in Gastrointestinal Medicine. 2015. Vol. 2015, no. 2015, pp.1-3.
https://search.emarefa.net/detail/BIM-1058536

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1058536