Recurrent C. difficile in a Patient with IgG Deficiency
Joint Authors
Jehangir, Asad
Bennett, Kyle
Fareedy, Shoaib Bilal
Rettew, Andrew
Shaikh, Bilal
Qureshi, Anam
Jehangir, Qasim
Alweis, Richard
Source
Case Reports in Gastrointestinal Medicine
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-04-05
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
IgG deficiency can predispose to recurrent pyogenic infections.
The association of IgG deficiency with Clostridium difficile infection has been infrequently reported in the literature.
We present a case of a middle-age woman with multiple hospitalizations for recurrent C.
difficile in a short span of time which prompted consideration of a possible fecal transplant.
On evaluation, she was found to have low total IgG, with subclass analysis revealing low IgG1 and IgG3.
She was started on monthly infusions of immunoglobulins and one year after her last episode of C.
difficile she has not had any recurrence.
The role of immunoglobulin infusion in the treatment of recurrent C.
difficile is controversial, with some studies revealing no clear evidence of benefit.
Our case report suggests that the patients who have underlying IgG deficiency may benefit from immunoglobulin, as this can significantly reduce the incidence of recurrent infections and hence save the healthcare costs.
American Psychological Association (APA)
Jehangir, Asad& Bennett, Kyle& Fareedy, Shoaib Bilal& Rettew, Andrew& Shaikh, Bilal& Qureshi, Anam…[et al.]. 2015. Recurrent C. difficile in a Patient with IgG Deficiency. Case Reports in Gastrointestinal Medicine،Vol. 2015, no. 2015, pp.1-3.
https://search.emarefa.net/detail/BIM-1058536
Modern Language Association (MLA)
Jehangir, Asad…[et al.]. Recurrent C. difficile in a Patient with IgG Deficiency. Case Reports in Gastrointestinal Medicine No. 2015 (2015), pp.1-3.
https://search.emarefa.net/detail/BIM-1058536
American Medical Association (AMA)
Jehangir, Asad& Bennett, Kyle& Fareedy, Shoaib Bilal& Rettew, Andrew& Shaikh, Bilal& Qureshi, Anam…[et al.]. Recurrent C. difficile in a Patient with IgG Deficiency. Case Reports in Gastrointestinal Medicine. 2015. Vol. 2015, no. 2015, pp.1-3.
https://search.emarefa.net/detail/BIM-1058536
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1058536