Renal and Neurological Response with Eculizumab in a Patient with Transplant Associated Thrombotic Microangiopathy after Allogeneic Hematopoietic Progenitor Cell Transplantation
Joint Authors
Sevindik, Ömür Gökmen
Alacacıoğlu, İnci
Katgı, Abdullah
Solmaz, Şerife Medeni
Acar, Celal
Pişkin, Özden
Özcan, Mehmet Ali
Demirkan, Fatih
Ündar, Bülent
Özsan, Güner Hayri
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-01-29
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Transplantation-associated thrombotic microangiopathy (TA-TMA) is a challenge after allogeneic hematopoietic progenitor cell transplantation, considering the diagnostic uncertainties and lack of established treatment.
We report a 43-year-old male patient who was diagnosed as TA-TMA after allogeneic progenitor cell transplantation for a progressive ALK negative anaplastic large cell lymphoma and responded to eculizumab with dramatically improving neurological status and renal function.
Rapid neurological and renal recovery achieved after eculizumab could support a possible relationship between complement activation and TA-TMA.
Eculizumab should be a reasonable treatment approach in patients with TA-TMA after allogeneic hematopoietic progenitor cell transplantation.
American Psychological Association (APA)
Sevindik, Ömür Gökmen& Alacacıoğlu, İnci& Katgı, Abdullah& Solmaz, Şerife Medeni& Acar, Celal& Pişkin, Özden…[et al.]. 2015. Renal and Neurological Response with Eculizumab in a Patient with Transplant Associated Thrombotic Microangiopathy after Allogeneic Hematopoietic Progenitor Cell Transplantation. Case Reports in Hematology،Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1058606
Modern Language Association (MLA)
Sevindik, Ömür Gökmen…[et al.]. Renal and Neurological Response with Eculizumab in a Patient with Transplant Associated Thrombotic Microangiopathy after Allogeneic Hematopoietic Progenitor Cell Transplantation. Case Reports in Hematology No. 2015 (2015), pp.1-4.
https://search.emarefa.net/detail/BIM-1058606
American Medical Association (AMA)
Sevindik, Ömür Gökmen& Alacacıoğlu, İnci& Katgı, Abdullah& Solmaz, Şerife Medeni& Acar, Celal& Pişkin, Özden…[et al.]. Renal and Neurological Response with Eculizumab in a Patient with Transplant Associated Thrombotic Microangiopathy after Allogeneic Hematopoietic Progenitor Cell Transplantation. Case Reports in Hematology. 2015. Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1058606
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1058606
