Treatment of Acquired von Willebrand Syndrome and Prevention of Bleeding Postautologous Stem Cell Transplant during Severe Pancytopenia with IVIG
Joint Authors
Zoghi, Behyar
Shaughnessy, Paul
Lyons, Roger M.
Helmer, Richard
Bachier, Carlos
LeMaistre, C. Frederick
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-04-02
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
The use of high dose chemotherapy followed by autologous hematopoietic stem cell transplantation for remission consolidation after initial induction represents standard of care for patients with multiple myeloma.
Patients with myeloma and Acquired von Willebrand Syndrome (AVWS) undergoing autologous stem cell transplant (ASCT) are at significant risk of bleeding due to the profound thrombocytopenia, low Factor VIII levels, fever, and toxicities associated with the preparative regimen.
We report a patient with AVWS associated with multiple myeloma who underwent autologous stem cell transplants as consolidation after initial induction and again at relapse.
He was successfully treated with high dose intravenous immunoglobulin (IVIG) prior to each transplant with rapid resolution of AVWS.
American Psychological Association (APA)
Zoghi, Behyar& Shaughnessy, Paul& Lyons, Roger M.& Helmer, Richard& Bachier, Carlos& LeMaistre, C. Frederick. 2015. Treatment of Acquired von Willebrand Syndrome and Prevention of Bleeding Postautologous Stem Cell Transplant during Severe Pancytopenia with IVIG. Case Reports in Hematology،Vol. 2015, no. 2015, pp.1-3.
https://search.emarefa.net/detail/BIM-1058639
Modern Language Association (MLA)
Zoghi, Behyar…[et al.]. Treatment of Acquired von Willebrand Syndrome and Prevention of Bleeding Postautologous Stem Cell Transplant during Severe Pancytopenia with IVIG. Case Reports in Hematology No. 2015 (2015), pp.1-3.
https://search.emarefa.net/detail/BIM-1058639
American Medical Association (AMA)
Zoghi, Behyar& Shaughnessy, Paul& Lyons, Roger M.& Helmer, Richard& Bachier, Carlos& LeMaistre, C. Frederick. Treatment of Acquired von Willebrand Syndrome and Prevention of Bleeding Postautologous Stem Cell Transplant during Severe Pancytopenia with IVIG. Case Reports in Hematology. 2015. Vol. 2015, no. 2015, pp.1-3.
https://search.emarefa.net/detail/BIM-1058639
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1058639