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Acute Promyelocytic Leukemia Presenting with Severe Marrow Fibrosis
Joint Authors
Shah, Harsh
Bradford, Carol
Sayar, Hamid
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-07-12
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
We report a case of acute promyelocytic leukemia (APL) presenting with severely fibrotic marrow.
There are four other reports of similar cases in the literature.
Our patient was treated with All-Transretinoic Acid- (ATRA-) containing induction chemotherapy, followed by consolidation and maintenance therapy.
He achieved a complete morphologic remission with adequate count recovery in a timely fashion, and later a molecular remission was documented.
The patient remains in molecular remission and demonstrates normal blood counts now more than 4 years after induction.
Since the morphological appearance may not be typical and the bone marrow may not yield an aspirate for cytogenetic analysis, awareness of such entity is important to make a correct diagnosis of this potentially curable disease.
American Psychological Association (APA)
Shah, Harsh& Bradford, Carol& Sayar, Hamid. 2015. Acute Promyelocytic Leukemia Presenting with Severe Marrow Fibrosis. Case Reports in Hematology،Vol. 2015, no. 2015, pp.1-3.
https://search.emarefa.net/detail/BIM-1058644
Modern Language Association (MLA)
Shah, Harsh…[et al.]. Acute Promyelocytic Leukemia Presenting with Severe Marrow Fibrosis. Case Reports in Hematology No. 2015 (2015), pp.1-3.
https://search.emarefa.net/detail/BIM-1058644
American Medical Association (AMA)
Shah, Harsh& Bradford, Carol& Sayar, Hamid. Acute Promyelocytic Leukemia Presenting with Severe Marrow Fibrosis. Case Reports in Hematology. 2015. Vol. 2015, no. 2015, pp.1-3.
https://search.emarefa.net/detail/BIM-1058644
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1058644