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Stabilisation of Laryngeal AL Amyloidosis with Long Term Curcumin Therapy
Joint Authors
Golombick, Terry
Diamond, Terrence H.
Manoharan, Arumugam
Ramakrishna, Rajeev
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-06-25
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Multiple myeloma (MM), smoldering myeloma (SMM), and monoclonal gammopathy of undetermined significance (MGUS) represent a spectrum of plasma cell dyscrasias (PCDs).
Immunoglobulin light chain amyloidosis (AL) falls within the spectrum of these diseases and has a mortality rate of more than 80% within 2 years of diagnosis.
Curcumin, derived from turmeric, has been shown to have a clinical benefit in some patients with PCDs.
In addition to a clinical benefit in these patients, curcumin has been found to have a strong affinity for fibrillar amyloid proteins.
We thus administered curcumin to a patient with laryngeal amyloidosis and smoldering myeloma and found that the patient has shown a lack of progression of his disease for a period of five years.
This is in keeping with our previous findings of clinical benefits of curcumin in patients with plasma cell dyscrasias.
We recommend further evaluation of curcumin in patients with primary AL amyloidosis.
American Psychological Association (APA)
Golombick, Terry& Diamond, Terrence H.& Manoharan, Arumugam& Ramakrishna, Rajeev. 2015. Stabilisation of Laryngeal AL Amyloidosis with Long Term Curcumin Therapy. Case Reports in Hematology،Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1058648
Modern Language Association (MLA)
Golombick, Terry…[et al.]. Stabilisation of Laryngeal AL Amyloidosis with Long Term Curcumin Therapy. Case Reports in Hematology No. 2015 (2015), pp.1-4.
https://search.emarefa.net/detail/BIM-1058648
American Medical Association (AMA)
Golombick, Terry& Diamond, Terrence H.& Manoharan, Arumugam& Ramakrishna, Rajeev. Stabilisation of Laryngeal AL Amyloidosis with Long Term Curcumin Therapy. Case Reports in Hematology. 2015. Vol. 2015, no. 2015, pp.1-4.
https://search.emarefa.net/detail/BIM-1058648
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1058648