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Heparin-Induced Thrombocytopenia in a Patient with Essential Thrombocythemia: A Case Based Update
Joint Authors
Abbas, Naeem
Noel, Edva
Skaradinskiy, Yevegeniy
Schreiber, Zwi
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-10-22
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Vascular thrombosis is a common clinical feature of both essential thrombocythemia (ET) and heparin-induced thrombocytopenia (HIT).
The development of HIT in a patient with ET is rare and underrecognized.
We report the case of a 77-year-old woman with preexisting ET, who was admitted with acute coronary syndrome, and IV heparin was started.
She was exposed to unfractionated heparin (UFH) 5 days prior to this admission.
Decrease in platelet count was noted, and HIT panel was sent.
Heparin was discontinued.
Patient developed atrial fibrillation, and Dabigatran was started.
On day three, patient also developed multiple tiny cerebral infarctions and acute right popliteal DVT.
On day ten of admission, HIT panel was positive, and Dabigatran was changed to Lepirudin.
Two days later, Lepirudin was also discontinued because patient developed pseudoaneurysm on the right common femoral artery at the site of cardiac catheterization access.
A progressive increase in the platelet count was noted after discontinuing heparin.
Physicians should be aware of the coexistence of HIT and ET, accompanied challenges of the prompt diagnosis, and initiation of appropriate treatment.
American Psychological Association (APA)
Noel, Edva& Abbas, Naeem& Skaradinskiy, Yevegeniy& Schreiber, Zwi. 2015. Heparin-Induced Thrombocytopenia in a Patient with Essential Thrombocythemia: A Case Based Update. Case Reports in Hematology،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1058657
Modern Language Association (MLA)
Noel, Edva…[et al.]. Heparin-Induced Thrombocytopenia in a Patient with Essential Thrombocythemia: A Case Based Update. Case Reports in Hematology No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1058657
American Medical Association (AMA)
Noel, Edva& Abbas, Naeem& Skaradinskiy, Yevegeniy& Schreiber, Zwi. Heparin-Induced Thrombocytopenia in a Patient with Essential Thrombocythemia: A Case Based Update. Case Reports in Hematology. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1058657
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1058657