Brain Abscess and Keratoacanthoma Suggestive of Hyper IgE Syndrome
Joint Authors
Alyasin, Soheyla
Amin, Reza
Teymoori, Alireza
Houshmand, Hamidreza
Houshmand, Gholamreza
Bahadoram, Mohammad
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-04-28
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Hyper immunoglobulin-E (IgE) syndrome is an autosomal immune deficiency disease.
It is characterized by an increase in IgE and eosinophil count with both T-cell and B-cell malfunction.
Here, we report an 8-year-old boy whose disease started with an unusual skin manifestation.
When 6 months old he developed generalized red, nontender nodules and pathologic report of the skin lesion was unremarkable (inflammatory).
Then he developed a painless, cold abscess.
At the age of 4 years, he developed a seronegative polyarticular arthritis.
Another skin biopsy was taken which was in favor of Keratoacanthoma.
Laboratory workup for immune deficiency showed high eosinophil count and high level of immunoglobulin-E, due to some diagnostic criteria (NIH sores: 41 in 9-year-olds), he was suggestive of hyper IgE syndrome.
At the age of 8, the patient developed an abscess in the left inguinal region.
While in hospital, the patient developed generalized tonic colonic convulsion and fever.
Brain computed tomography scan revealed an abscess in the right frontal lobe.
Subsequently magnetic resonance imaging (MRI) of the brain indicated expansion of the existing abscess to contralateral frontal lobe (left side).
After evacuating the abscesses and administrating intravenous antibiotic, the patient’s condition improved dramatically and fever stopped.
American Psychological Association (APA)
Alyasin, Soheyla& Amin, Reza& Teymoori, Alireza& Houshmand, Hamidreza& Houshmand, Gholamreza& Bahadoram, Mohammad. 2015. Brain Abscess and Keratoacanthoma Suggestive of Hyper IgE Syndrome. Case Reports in Immunology،Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1058674
Modern Language Association (MLA)
Alyasin, Soheyla…[et al.]. Brain Abscess and Keratoacanthoma Suggestive of Hyper IgE Syndrome. Case Reports in Immunology No. 2015 (2015), pp.1-5.
https://search.emarefa.net/detail/BIM-1058674
American Medical Association (AMA)
Alyasin, Soheyla& Amin, Reza& Teymoori, Alireza& Houshmand, Hamidreza& Houshmand, Gholamreza& Bahadoram, Mohammad. Brain Abscess and Keratoacanthoma Suggestive of Hyper IgE Syndrome. Case Reports in Immunology. 2015. Vol. 2015, no. 2015, pp.1-5.
https://search.emarefa.net/detail/BIM-1058674
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1058674