Life Threatening Idiopathic Recurrent Angioedema Responding to Cannabis
Joint Authors
Borer, Abraham
Roy-Shapira, Aviel
Brotfain, Evgeni
Klein, Moti
Frenkel, Amit
Koyfman, Leonid
Source
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-07-16
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
We present a case of a 27-year-old man with recurrent episodes of angioedema since he was 19, who responded well to treatment with medical grade cannabis.
Initially, he responded to steroids and antihistamines, but several attempts to withdraw treatment resulted in recurrence.
In the last few months before prescribing cannabis, the frequency and severity of the attacks worsened and included several presyncope events, associated with scrotal and neck swelling.
No predisposing factors were identified, and extensive workup was negative.
The patient reported that he was periodically using cannabis socially and that during these periods he was free of attacks.
Recent data suggest that cannabis derivatives are involved in the control of mast cell activation.
Consequently, we decided to try a course of inhaled cannabis as modulators of immune cell functions.
The use of inhaled cannabis resulted in a complete response, and he has been free of symptoms for 2 years.
An attempt to withhold the inhaled cannabis led to a recurrent attack within a week, and resuming cannabis maintained the remission, suggesting a cause and effect relationship.
American Psychological Association (APA)
Frenkel, Amit& Roy-Shapira, Aviel& Brotfain, Evgeni& Koyfman, Leonid& Borer, Abraham& Klein, Moti. 2015. Life Threatening Idiopathic Recurrent Angioedema Responding to Cannabis. Case Reports in Immunology،Vol. 2015, no. 2015, pp.1-3.
https://search.emarefa.net/detail/BIM-1058679
Modern Language Association (MLA)
Frenkel, Amit…[et al.]. Life Threatening Idiopathic Recurrent Angioedema Responding to Cannabis. Case Reports in Immunology No. 2015 (2015), pp.1-3.
https://search.emarefa.net/detail/BIM-1058679
American Medical Association (AMA)
Frenkel, Amit& Roy-Shapira, Aviel& Brotfain, Evgeni& Koyfman, Leonid& Borer, Abraham& Klein, Moti. Life Threatening Idiopathic Recurrent Angioedema Responding to Cannabis. Case Reports in Immunology. 2015. Vol. 2015, no. 2015, pp.1-3.
https://search.emarefa.net/detail/BIM-1058679
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1058679