Pseudomonas aeruginosa Acquisition in Cystic Fibrosis Patients in Context of Otorhinolaryngological Surgery or Dentist Attendance: Case Series and Discussion of Preventive Concepts
Joint Authors
Mainz, Jochen G.
Gerber, Andrea
Lorenz, Michael
Michl, Ruth
Hentschel, Julia
Nader, Anika
Beck, James F.
Mueller, Andreas H.
Pletz, Mathias Wilhelm
Source
Case Reports in Infectious Diseases
Issue
Vol. 2015, Issue 2015 (31 Dec. 2015), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-03-18
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Introduction.
P.
aeruginosa is the primary cause for pulmonary destruction and premature death in cystic fibrosis (CF).
Therefore, prevention of airway colonization with the pathogen, ubiquitously present in water, is essential.
Infection of CF patients with P.
aeruginosa after dentist treatment was proven and dental unit waterlines were identified as source, suggesting prophylactic measures.
For their almost regular sinonasal involvement, CF patients often require otorhinolaryngological (ORL) attendance.
Despite some fields around ORL-procedures with comparable risk for acquisition of P.
aeruginosa, such CF cases have not yet been reported.
We present four CF patients, who primarily acquired P.
aeruginosa around ORL surgery, and one around dentist treatment.
Additionally, we discuss risks and preventive strategies for CF patients undergoing ORL-treatment.
Perils include contact to pathogen-carriers in waiting rooms, instrumentation, suction, drilling, and flushing fluid, when droplets containing pathogens can be nebulized.
Postsurgery mucosal damage and debridement impair sinonasal mucociliary clearance, facilitating pathogen proliferation and infestation.
Therefore, sinonasal surgery and dentist treatment of CF patients without chronic P.
aeruginosa colonization must be linked to repeated microbiological assessment.
Further studies must elaborate whether all CF patients undergoing ORL-surgery require antipseudomonal prophylaxis, including nasal lavages containing antibiotics.
Altogether, this underestimated risk requires structured prevention protocols.
American Psychological Association (APA)
Mainz, Jochen G.& Gerber, Andrea& Lorenz, Michael& Michl, Ruth& Hentschel, Julia& Nader, Anika…[et al.]. 2015. Pseudomonas aeruginosa Acquisition in Cystic Fibrosis Patients in Context of Otorhinolaryngological Surgery or Dentist Attendance: Case Series and Discussion of Preventive Concepts. Case Reports in Infectious Diseases،Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1058714
Modern Language Association (MLA)
Mainz, Jochen G.…[et al.]. Pseudomonas aeruginosa Acquisition in Cystic Fibrosis Patients in Context of Otorhinolaryngological Surgery or Dentist Attendance: Case Series and Discussion of Preventive Concepts. Case Reports in Infectious Diseases No. 2015 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1058714
American Medical Association (AMA)
Mainz, Jochen G.& Gerber, Andrea& Lorenz, Michael& Michl, Ruth& Hentschel, Julia& Nader, Anika…[et al.]. Pseudomonas aeruginosa Acquisition in Cystic Fibrosis Patients in Context of Otorhinolaryngological Surgery or Dentist Attendance: Case Series and Discussion of Preventive Concepts. Case Reports in Infectious Diseases. 2015. Vol. 2015, no. 2015, pp.1-9.
https://search.emarefa.net/detail/BIM-1058714
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1058714